THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS

Objective: To explore the use of therapeutic plasma exchange as adjunctive therapy in COVID-19 patients with and without diabetes mellitus. Study Design: Prospective, observational study. Place and Duration of Study: Pakistan Emirates Military Hospital Rawalpindi, from Jan to Feb 2021. Meth...

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Autores principales:	Komal Arshad, Zill-e-Humayun ., Sultan Mehmood Kamran, Ikram Khaliq, Muhammad Raza Asif, Saman Tanveer
Formato:	article
Lenguaje:	EN
Publicado:	Army Medical College Rawalpindi 2021
Materias:	covid-19 diabetes Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8a4cff560c044cfc8a067bc25e827817
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spelling	oai:doaj.org-article:8a4cff560c044cfc8a067bc25e8278172021-11-23T03:25:39ZTHE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS0030-96482411-8842https://doaj.org/article/8a4cff560c044cfc8a067bc25e8278172021-10-01T00:00:00Zhttps://www.pafmj.org/index.php/PAFMJ/article/view/6317/3610https://doaj.org/toc/0030-9648https://doaj.org/toc/2411-8842Objective: To explore the use of therapeutic plasma exchange as adjunctive therapy in COVID-19 patients with and without diabetes mellitus. Study Design: Prospective, observational study. Place and Duration of Study: Pakistan Emirates Military Hospital Rawalpindi, from Jan to Feb 2021. Methodology: A total of 90 male patients with laboratory-confirmed coronavirus infection were selected based on our inclusion criteria and their management and outcomes were recorded. The data were analyzed using SPSS-22 and Microsoft Excel. Results: The mortality rate was lower in patients who received 1 or more sessions of plasma exchange compared to those who did not receive plasma exchange (7.5% vs 12%). A lower mortality rate was seen in patients without diabetes who received therapeutic plasma exchange in addition to standard therapy compared to patients who received standard therapy alone (0 vs 14.82%, p=0.112). In patients with diabetes, a higher mortality rate was found in the group that had received therapeutic plasma exchange in addition to standard therapy instead of standard therapy alone (20% vs 8.7%, p=0.365). Conclusion: Overall our study supports the use of therapeutic plasma exchange in COVID-19 patients. However, although statistically insignificant, there appears to be a higher mortality rate in patients with diabetes who received therapeutic plasma exchange in addition to standard therapy. As such, we recommend further investigation of this aspect.Komal ArshadZill-e-Humayun .Sultan Mehmood KamranIkram KhaliqMuhammad Raza AsifSaman TanveerArmy Medical College Rawalpindiarticlecovid-19diabetesMedicineRMedicine (General)R5-920ENPakistan Armed Forces Medical Journal, Vol 71, Iss 5, Pp 1732-1735 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	covid-19 diabetes Medicine R Medicine (General) R5-920
spellingShingle	covid-19 diabetes Medicine R Medicine (General) R5-920 Komal Arshad Zill-e-Humayun . Sultan Mehmood Kamran Ikram Khaliq Muhammad Raza Asif Saman Tanveer THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
description	Objective: To explore the use of therapeutic plasma exchange as adjunctive therapy in COVID-19 patients with and without diabetes mellitus. Study Design: Prospective, observational study. Place and Duration of Study: Pakistan Emirates Military Hospital Rawalpindi, from Jan to Feb 2021. Methodology: A total of 90 male patients with laboratory-confirmed coronavirus infection were selected based on our inclusion criteria and their management and outcomes were recorded. The data were analyzed using SPSS-22 and Microsoft Excel. Results: The mortality rate was lower in patients who received 1 or more sessions of plasma exchange compared to those who did not receive plasma exchange (7.5% vs 12%). A lower mortality rate was seen in patients without diabetes who received therapeutic plasma exchange in addition to standard therapy compared to patients who received standard therapy alone (0 vs 14.82%, p=0.112). In patients with diabetes, a higher mortality rate was found in the group that had received therapeutic plasma exchange in addition to standard therapy instead of standard therapy alone (20% vs 8.7%, p=0.365). Conclusion: Overall our study supports the use of therapeutic plasma exchange in COVID-19 patients. However, although statistically insignificant, there appears to be a higher mortality rate in patients with diabetes who received therapeutic plasma exchange in addition to standard therapy. As such, we recommend further investigation of this aspect.
format	article
author	Komal Arshad Zill-e-Humayun . Sultan Mehmood Kamran Ikram Khaliq Muhammad Raza Asif Saman Tanveer
author_facet	Komal Arshad Zill-e-Humayun . Sultan Mehmood Kamran Ikram Khaliq Muhammad Raza Asif Saman Tanveer
author_sort	Komal Arshad
title	THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
title_short	THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
title_full	THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
title_fullStr	THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
title_full_unstemmed	THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS
title_sort	efficacy of plasma exchange in covid-19 patients with comorbid diabetes mellitus
publisher	Army Medical College Rawalpindi
publishDate	2021
url	https://doaj.org/article/8a4cff560c044cfc8a067bc25e827817
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THE EFFICACY OF PLASMA EXCHANGE IN COVID-19 PATIENTS WITH COMORBID DIABETES MELLITUS

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