CaMKII activation in early diabetic hearts induces altered sarcoplasmic reticulum-mitochondria signaling

CaMKII activation in early diabetic hearts induces altered sarcoplasmic reticulum-mitochondria signaling

Abstract Prediabetic myocardium, induced by fructose-rich diet (FRD), is prone to increased sarcoplasmic reticulum (SR)-Ca2+ leak and arrhythmias due to increased activity of the Ca2+/calmodulin protein kinase II (CaMKII). However, little is known about the role of SR-mitochondria microdomains, mito...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Marilen Federico, Maite Zavala, Tamara Vico, Sofía López, Enrique Portiansky, Silvia Alvarez, Maria Celeste Villa Abrille, Julieta Palomeque
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/8a54e36dee0342b9aa851469f3efb5b0
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares