Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK

Abstract The study aims to evaluate, using the Iterative Closest Point (ICP) algorithm, the repeatability of successive corneal elevation measurements taken post-LASIK. Two topography maps of 98 LASIK participants were recorded preoperatively (Pre), 1 month (Pos1M) and 3 months postoperatively (Pos3...

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Autores principales:	XiaoBo Zheng, WeiHua Yang, LiFang Huang, JunJie Wang, Si Cao, Brendan Geraghty, YiPing Zhao, QinMei Wang, FangJun Bao, Ahmed Elsheikh
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8a55845de3f34e6ea23bd27ad892decb
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spelling	oai:doaj.org-article:8a55845de3f34e6ea23bd27ad892decb2021-12-02T16:06:12ZEvaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK10.1038/s41598-017-03223-92045-2322https://doaj.org/article/8a55845de3f34e6ea23bd27ad892decb2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41598-017-03223-9https://doaj.org/toc/2045-2322Abstract The study aims to evaluate, using the Iterative Closest Point (ICP) algorithm, the repeatability of successive corneal elevation measurements taken post-LASIK. Two topography maps of 98 LASIK participants were recorded preoperatively (Pre), 1 month (Pos1M) and 3 months postoperatively (Pos3M). Elevation of the second measurement was fitted to the first measurement by calculating using ICP, and correcting for, both translational and rotational misalignment components. The RMS of elevation differences between anterior corneal measurements were statistically significant post-LASIK compared to preoperation (P < 0.05). A misalignment ratio used to describe the weighting of the elevation difference caused by misalignment relative to the total difference remained stable (0.40 and 0.23 for anterior and posterior corneal surfaces, respectively) in different periods. The study also considered the combined misalignment parameter (CM), which represents the total effect of all individual misalignment components on the repeatability of corneal topography maps. CM was significantly greater post-LASIK relative to pre-LASIK (P < 0.05). Overall, the contribution of misalignment to the total difference between successive corneal measurements remained stable pre and post operation, while the combined effect of refractive error correction and optical diameter appeared to have a significant influence on the elevation repeatability in the early stages of the follow up period.XiaoBo ZhengWeiHua YangLiFang HuangJunJie WangSi CaoBrendan GeraghtyYiPing ZhaoQinMei WangFangJun BaoAhmed ElsheikhNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 7, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q XiaoBo Zheng WeiHua Yang LiFang Huang JunJie Wang Si Cao Brendan Geraghty YiPing Zhao QinMei Wang FangJun Bao Ahmed Elsheikh Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
description	Abstract The study aims to evaluate, using the Iterative Closest Point (ICP) algorithm, the repeatability of successive corneal elevation measurements taken post-LASIK. Two topography maps of 98 LASIK participants were recorded preoperatively (Pre), 1 month (Pos1M) and 3 months postoperatively (Pos3M). Elevation of the second measurement was fitted to the first measurement by calculating using ICP, and correcting for, both translational and rotational misalignment components. The RMS of elevation differences between anterior corneal measurements were statistically significant post-LASIK compared to preoperation (P < 0.05). A misalignment ratio used to describe the weighting of the elevation difference caused by misalignment relative to the total difference remained stable (0.40 and 0.23 for anterior and posterior corneal surfaces, respectively) in different periods. The study also considered the combined misalignment parameter (CM), which represents the total effect of all individual misalignment components on the repeatability of corneal topography maps. CM was significantly greater post-LASIK relative to pre-LASIK (P < 0.05). Overall, the contribution of misalignment to the total difference between successive corneal measurements remained stable pre and post operation, while the combined effect of refractive error correction and optical diameter appeared to have a significant influence on the elevation repeatability in the early stages of the follow up period.
format	article
author	XiaoBo Zheng WeiHua Yang LiFang Huang JunJie Wang Si Cao Brendan Geraghty YiPing Zhao QinMei Wang FangJun Bao Ahmed Elsheikh
author_facet	XiaoBo Zheng WeiHua Yang LiFang Huang JunJie Wang Si Cao Brendan Geraghty YiPing Zhao QinMei Wang FangJun Bao Ahmed Elsheikh
author_sort	XiaoBo Zheng
title	Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
title_short	Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
title_full	Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
title_fullStr	Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
title_full_unstemmed	Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK
title_sort	evaluating the repeatability of corneal elevation through calculating the misalignment between successive topography measurements during the follow up of lasik
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8a55845de3f34e6ea23bd27ad892decb
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Evaluating the repeatability of corneal elevation through calculating the misalignment between Successive topography measurements during the follow up of LASIK

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