Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report

Mvuyo Maqhawe Sikhondze,1 Carlos Cabrera Dreque,1 Edson Tayebwa,1 Gotharido Tumubugane,1 Charles Newton Odongo,1 Eugene Ogwang2 1Department of Surgery, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, Uganda; 2Department of Radiology, Mbarara University of Science an...

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Autores principales: Sikhondze MM, Cabrera Dreque C, Tayebwa E, Tumubugane G, Odongo CN, Ogwang E
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Publicado: Dove Medical Press 2021
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spelling oai:doaj.org-article:8a64c2ef46bd4f1ead02b712b3aad5202021-11-23T18:43:00ZGiant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report1179-142Xhttps://doaj.org/article/8a64c2ef46bd4f1ead02b712b3aad5202021-11-01T00:00:00Zhttps://www.dovepress.com/giant-choledochal-cyst-in-an-adult-at-a-teaching-hospital-in-south-wes-peer-reviewed-fulltext-article-IMCRJhttps://doaj.org/toc/1179-142XMvuyo Maqhawe Sikhondze,1 Carlos Cabrera Dreque,1 Edson Tayebwa,1 Gotharido Tumubugane,1 Charles Newton Odongo,1 Eugene Ogwang2 1Department of Surgery, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, Uganda; 2Department of Radiology, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, UgandaCorrespondence: Mvuyo Maqhawe SikhondzeDepartment of Surgery, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, UgandaTel +256 48 542 0785Fax +256 48 542 0782Email maqhawesikhondze@yahoo.co.ukBackground: Choledochal cysts are rare congenital malformations characterized by cystic dilatations of the biliary tree. They are more prevalent in East Asian populations, but uncommon in western countries, and scarcely reported in African nations. They are classically diagnosed in children, and only 20– 30% of cases are diagnosed in adulthood. Giant choledochal cysts are those with sizes exceeding 10cm, and are extremely rare with a few reported in the literature, thus the need for this case report.Case: A 25-year-old Ugandan woman presented with an 8-month history of abdominal pain, jaundice and progressively increasing right upper quadrant abdominal mass. She underwent trans-abdominal ultrasonography that revealed a large, well-defined, echo-free mass in the right upper quadrant, extending to the lumbar region. Abdominal computed tomography (CT) revealed a huge thin-walled, cystic mass rising from the right wall of common hepatic duct, displacing the surrounding structures and no visible common bile duct. Complete cyst excision of a giant choledochal cyst type IVa was performed without decompression, in addition to cholecystectomy and reconstruction with hepaticojejunostomy and jejunojejunostomy anastomoses.Conclusion: Giant choledochal cysts are a very rare pathology worldwide. Diagnosis can still be made using ultrasound and CT where more advanced imaging modalities like endoscopic retrograde cholangiopancreatography (ERCP) are not available. Complete surgical resection of giant choledochal cysts is surgically challenging, but essential to relieve symptoms and prevent malignant transformation. To the best of our knowledge, this is the first reported case in the literature, of a giant choledochal cyst that was successfully treated in an African nation.Keywords: giant choledochal cyst, choledochal cyst, Todani’s classificationSikhondze MMCabrera Dreque CTayebwa ETumubugane GOdongo CNOgwang EDove Medical Pressarticlegiant choledochal cystcholedochal cysttodani’s classificationMedicine (General)R5-920ENInternational Medical Case Reports Journal, Vol Volume 14, Pp 789-795 (2021)
institution DOAJ
collection DOAJ
language EN
topic giant choledochal cyst
choledochal cyst
todani’s classification
Medicine (General)
R5-920
spellingShingle giant choledochal cyst
choledochal cyst
todani’s classification
Medicine (General)
R5-920
Sikhondze MM
Cabrera Dreque C
Tayebwa E
Tumubugane G
Odongo CN
Ogwang E
Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
description Mvuyo Maqhawe Sikhondze,1 Carlos Cabrera Dreque,1 Edson Tayebwa,1 Gotharido Tumubugane,1 Charles Newton Odongo,1 Eugene Ogwang2 1Department of Surgery, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, Uganda; 2Department of Radiology, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, UgandaCorrespondence: Mvuyo Maqhawe SikhondzeDepartment of Surgery, Mbarara University of Science and Technology, Mbarara City, South-Western Uganda, UgandaTel +256 48 542 0785Fax +256 48 542 0782Email maqhawesikhondze@yahoo.co.ukBackground: Choledochal cysts are rare congenital malformations characterized by cystic dilatations of the biliary tree. They are more prevalent in East Asian populations, but uncommon in western countries, and scarcely reported in African nations. They are classically diagnosed in children, and only 20– 30% of cases are diagnosed in adulthood. Giant choledochal cysts are those with sizes exceeding 10cm, and are extremely rare with a few reported in the literature, thus the need for this case report.Case: A 25-year-old Ugandan woman presented with an 8-month history of abdominal pain, jaundice and progressively increasing right upper quadrant abdominal mass. She underwent trans-abdominal ultrasonography that revealed a large, well-defined, echo-free mass in the right upper quadrant, extending to the lumbar region. Abdominal computed tomography (CT) revealed a huge thin-walled, cystic mass rising from the right wall of common hepatic duct, displacing the surrounding structures and no visible common bile duct. Complete cyst excision of a giant choledochal cyst type IVa was performed without decompression, in addition to cholecystectomy and reconstruction with hepaticojejunostomy and jejunojejunostomy anastomoses.Conclusion: Giant choledochal cysts are a very rare pathology worldwide. Diagnosis can still be made using ultrasound and CT where more advanced imaging modalities like endoscopic retrograde cholangiopancreatography (ERCP) are not available. Complete surgical resection of giant choledochal cysts is surgically challenging, but essential to relieve symptoms and prevent malignant transformation. To the best of our knowledge, this is the first reported case in the literature, of a giant choledochal cyst that was successfully treated in an African nation.Keywords: giant choledochal cyst, choledochal cyst, Todani’s classification
format article
author Sikhondze MM
Cabrera Dreque C
Tayebwa E
Tumubugane G
Odongo CN
Ogwang E
author_facet Sikhondze MM
Cabrera Dreque C
Tayebwa E
Tumubugane G
Odongo CN
Ogwang E
author_sort Sikhondze MM
title Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
title_short Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
title_full Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
title_fullStr Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
title_full_unstemmed Giant Choledochal Cyst in an Adult at a Teaching Hospital in South-Western Uganda: A Case Report
title_sort giant choledochal cyst in an adult at a teaching hospital in south-western uganda: a case report
publisher Dove Medical Press
publishDate 2021
url https://doaj.org/article/8a64c2ef46bd4f1ead02b712b3aad520
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