A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device

Abstract Background Intensity-modulated radiation therapy (IMRT) and volume-modulated arc therapy (VMAT) are rather complex treatment techniques and require patient-specific quality assurance procedures. Electronic portal imaging devices (EPID) are increasingly used in the verification of radiation...

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Autores principales:	Jun Zhang, Xiuqing Li, Miaomiao Lu, Qilin Zhang, Xile Zhang, Ruijie Yang, Maria F. Chan, Junhai Wen
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Radiotherapy EPID Quality assurance In vivo verification Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Acceso en línea:	https://doaj.org/article/8a6b69922d3648009b84aa31c77f1ac1
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spelling	oai:doaj.org-article:8a6b69922d3648009b84aa31c77f1ac12021-12-05T12:10:23ZA method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device10.1186/s13014-021-01953-91748-717Xhttps://doaj.org/article/8a6b69922d3648009b84aa31c77f1ac12021-12-01T00:00:00Zhttps://doi.org/10.1186/s13014-021-01953-9https://doaj.org/toc/1748-717XAbstract Background Intensity-modulated radiation therapy (IMRT) and volume-modulated arc therapy (VMAT) are rather complex treatment techniques and require patient-specific quality assurance procedures. Electronic portal imaging devices (EPID) are increasingly used in the verification of radiation therapy (RT). This work aims to develop a novel model to predict the EPID transmission image (TI) with fluence maps from the RT plan. The predicted TI is compared with the measured TI for in vivo treatment verification. Methods The fluence map was extracted from the RT plan and corrections of penumbra, response, global field output, attenuation, and scatter were applied before the TI was calculated. The parameters used in the model were calculated separately for central axis and off-axis points using a series of EPID measurement data. Our model was evaluated using a CIRS thorax phantom and 20 clinical plans (10 IMRT and 10 VMAT) optimized for head and neck, breast, and rectum treatments. Results Comparisons of the predicted and measured images were carried out using a global gamma analysis of 3%/2 mm (10% threshold) to validate the accuracy of the model. The gamma pass rates for IMRT and VMAT were greater than 97.2% and 94.5% at 3%/2 mm, respectively. Conclusion We have developed an accurate and straightforward EPID-based quality assurance model that can potentially be used for in vivo treatment verification of the IMRT and VMAT delivery.Jun ZhangXiuqing LiMiaomiao LuQilin ZhangXile ZhangRuijie YangMaria F. ChanJunhai WenBMCarticleRadiotherapyEPIDQuality assuranceIn vivo verificationMedical physics. Medical radiology. Nuclear medicineR895-920Neoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENRadiation Oncology, Vol 16, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Radiotherapy EPID Quality assurance In vivo verification Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
spellingShingle	Radiotherapy EPID Quality assurance In vivo verification Medical physics. Medical radiology. Nuclear medicine R895-920 Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Jun Zhang Xiuqing Li Miaomiao Lu Qilin Zhang Xile Zhang Ruijie Yang Maria F. Chan Junhai Wen A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
description	Abstract Background Intensity-modulated radiation therapy (IMRT) and volume-modulated arc therapy (VMAT) are rather complex treatment techniques and require patient-specific quality assurance procedures. Electronic portal imaging devices (EPID) are increasingly used in the verification of radiation therapy (RT). This work aims to develop a novel model to predict the EPID transmission image (TI) with fluence maps from the RT plan. The predicted TI is compared with the measured TI for in vivo treatment verification. Methods The fluence map was extracted from the RT plan and corrections of penumbra, response, global field output, attenuation, and scatter were applied before the TI was calculated. The parameters used in the model were calculated separately for central axis and off-axis points using a series of EPID measurement data. Our model was evaluated using a CIRS thorax phantom and 20 clinical plans (10 IMRT and 10 VMAT) optimized for head and neck, breast, and rectum treatments. Results Comparisons of the predicted and measured images were carried out using a global gamma analysis of 3%/2 mm (10% threshold) to validate the accuracy of the model. The gamma pass rates for IMRT and VMAT were greater than 97.2% and 94.5% at 3%/2 mm, respectively. Conclusion We have developed an accurate and straightforward EPID-based quality assurance model that can potentially be used for in vivo treatment verification of the IMRT and VMAT delivery.
format	article
author	Jun Zhang Xiuqing Li Miaomiao Lu Qilin Zhang Xile Zhang Ruijie Yang Maria F. Chan Junhai Wen
author_facet	Jun Zhang Xiuqing Li Miaomiao Lu Qilin Zhang Xile Zhang Ruijie Yang Maria F. Chan Junhai Wen
author_sort	Jun Zhang
title	A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
title_short	A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
title_full	A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
title_fullStr	A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
title_full_unstemmed	A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device
title_sort	method for in vivo treatment verification of imrt and vmat based on electronic portal imaging device
publisher	BMC
publishDate	2021
url	https://doaj.org/article/8a6b69922d3648009b84aa31c77f1ac1
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_version_	1718372203773296640

A method for in vivo treatment verification of IMRT and VMAT based on electronic portal imaging device

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