The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis

Background. Pitted keratolysis (PK) is a superficial bacterial infection diagnosed mainly by clinical manifestations. Current data on its dermoscopic and histopathological findings, and the correlation of those findings, are limited. Objectives. To evaluate the clinical manifestations, dermoscopic,...

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Autores principales:	Penvadee Pattanaprichakul, Kanokvalai Kulthanan, Sumanas Bunyaratavej, Sasima Eimpunth, Thanaporn Rungruang, Pattriya Chanyachailert, Punyawee Ongsri, Poramin Patthamalai, Kanyalak Munprom, Charussri Leeyaphan
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/8a716f561b9642a6b38189473134e5b3
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spelling	oai:doaj.org-article:8a716f561b9642a6b38189473134e5b32021-11-08T02:35:15ZThe Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis2314-614110.1155/2021/3416643https://doaj.org/article/8a716f561b9642a6b38189473134e5b32021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/3416643https://doaj.org/toc/2314-6141Background. Pitted keratolysis (PK) is a superficial bacterial infection diagnosed mainly by clinical manifestations. Current data on its dermoscopic and histopathological findings, and the correlation of those findings, are limited. Objectives. To evaluate the clinical manifestations, dermoscopic, and histopathological findings of PK and to determine the correlations. Methods. Forty naval cadets with PK and five cadets with normal feet were enrolled this cohort study and provided informed consent. Dermoscopy was independently applied and evaluated by 2 dermatologists. Shave biopsies were performed on 37 patients with PK. Results. Pits were the most common dermoscopic finding (88.1%). The dermoscope had more sensitivity for the detection of PK than the naked eye examinations. Apart from the pits and the presence of bacteria, the most common histopathological finding for PK was color alteration of keratin. The presence of bacteria correlated with interrupted dermatoglyphic lines and the color alteration of keratin. Moreover, the presence of bacteria at the base of pits was related to worse treatment outcomes. Conclusions. Dermoscopy is a useful tool for PK diagnosis. Color alteration of keratin is another histopathological finding for PK. The presence of bacteria is associated with worse treatment outcomes.Penvadee PattanaprichakulKanokvalai KulthananSumanas BunyaratavejSasima EimpunthThanaporn RungruangPattriya ChanyachailertPunyawee OngsriPoramin PatthamalaiKanyalak MunpromCharussri LeeyaphanHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Penvadee Pattanaprichakul Kanokvalai Kulthanan Sumanas Bunyaratavej Sasima Eimpunth Thanaporn Rungruang Pattriya Chanyachailert Punyawee Ongsri Poramin Patthamalai Kanyalak Munprom Charussri Leeyaphan The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
description	Background. Pitted keratolysis (PK) is a superficial bacterial infection diagnosed mainly by clinical manifestations. Current data on its dermoscopic and histopathological findings, and the correlation of those findings, are limited. Objectives. To evaluate the clinical manifestations, dermoscopic, and histopathological findings of PK and to determine the correlations. Methods. Forty naval cadets with PK and five cadets with normal feet were enrolled this cohort study and provided informed consent. Dermoscopy was independently applied and evaluated by 2 dermatologists. Shave biopsies were performed on 37 patients with PK. Results. Pits were the most common dermoscopic finding (88.1%). The dermoscope had more sensitivity for the detection of PK than the naked eye examinations. Apart from the pits and the presence of bacteria, the most common histopathological finding for PK was color alteration of keratin. The presence of bacteria correlated with interrupted dermatoglyphic lines and the color alteration of keratin. Moreover, the presence of bacteria at the base of pits was related to worse treatment outcomes. Conclusions. Dermoscopy is a useful tool for PK diagnosis. Color alteration of keratin is another histopathological finding for PK. The presence of bacteria is associated with worse treatment outcomes.
format	article
author	Penvadee Pattanaprichakul Kanokvalai Kulthanan Sumanas Bunyaratavej Sasima Eimpunth Thanaporn Rungruang Pattriya Chanyachailert Punyawee Ongsri Poramin Patthamalai Kanyalak Munprom Charussri Leeyaphan
author_facet	Penvadee Pattanaprichakul Kanokvalai Kulthanan Sumanas Bunyaratavej Sasima Eimpunth Thanaporn Rungruang Pattriya Chanyachailert Punyawee Ongsri Poramin Patthamalai Kanyalak Munprom Charussri Leeyaphan
author_sort	Penvadee Pattanaprichakul
title	The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
title_short	The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
title_full	The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
title_fullStr	The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
title_full_unstemmed	The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis
title_sort	correlations between clinical features, dermoscopic and histopathological findings, and treatment outcomes of patients with pitted keratolysis
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/8a716f561b9642a6b38189473134e5b3
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The Correlations between Clinical Features, Dermoscopic and Histopathological Findings, and Treatment Outcomes of Patients with Pitted Keratolysis

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