A Natural Deep Eutectic Solvent Formulated to Stabilize β-Lactam Antibiotics
Abstract β-lactam antibiotics, such as penicillin share a very unstable chemical structure. In water-based solutions, such as those used for clinical applications, the β-lactam ring is readily opened due to a nucleophilic or electrophilic attack, leading to the loss of antimicrobial activity. Since...
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Autores principales: | Belén Olivares, Fabián Martínez, Lina Rivas, Cristian Calderón, José M. Munita, Paola R. Campodonico |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/8a7d505fc0ac42ab8e6ac7288c1ae786 |
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