Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain

Probiotics have been associated with clinical infections, toxicity, and antimicrobial resistance transfer, raising public concerns. Probiotic enterococci are emerging food risks as opportunistic pathogens, yet little attention has been paid to them. Herein, we collected 88 enterococcal isolates from...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Wenjiao Xu, Yuwen Fang, Qiao Hu, Kui Zhu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	probiotic enterococci toxicity antimicrobial resistance Chemical technology TP1-1185
Acceso en línea:	https://doaj.org/article/8a8013455d314ab9b5e8b6c31f421a70
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8a8013455d314ab9b5e8b6c31f421a70
record_format	dspace
spelling	oai:doaj.org-article:8a8013455d314ab9b5e8b6c31f421a702021-11-25T17:36:23ZEmerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain10.3390/foods101128462304-8158https://doaj.org/article/8a8013455d314ab9b5e8b6c31f421a702021-11-01T00:00:00Zhttps://www.mdpi.com/2304-8158/10/11/2846https://doaj.org/toc/2304-8158Probiotics have been associated with clinical infections, toxicity, and antimicrobial resistance transfer, raising public concerns. Probiotic enterococci are emerging food risks as opportunistic pathogens, yet little attention has been paid to them. Herein, we collected 88 enterococcal isolates from probiotic products used for humans, companion animals, livestock, and aquaculture. Results showed that all 88 probiotic enterococcal isolates harbored diverse virulence genes, multiple antimicrobial resistance genes, and mobile genetic elements. Notably, 77 isolates were highly resistant to gentamicin. Representative enterococcal isolates exerted toxic activities in both in vitro and in vivo models. Collectively, our findings suggest that probiotic enterococci may be harmful to hosts and pose a potential threat to public health.Wenjiao XuYuwen FangQiao HuKui ZhuMDPI AGarticleprobioticenterococcitoxicityantimicrobial resistanceChemical technologyTP1-1185ENFoods, Vol 10, Iss 2846, p 2846 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	probiotic enterococci toxicity antimicrobial resistance Chemical technology TP1-1185
spellingShingle	probiotic enterococci toxicity antimicrobial resistance Chemical technology TP1-1185 Wenjiao Xu Yuwen Fang Qiao Hu Kui Zhu Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
description	Probiotics have been associated with clinical infections, toxicity, and antimicrobial resistance transfer, raising public concerns. Probiotic enterococci are emerging food risks as opportunistic pathogens, yet little attention has been paid to them. Herein, we collected 88 enterococcal isolates from probiotic products used for humans, companion animals, livestock, and aquaculture. Results showed that all 88 probiotic enterococcal isolates harbored diverse virulence genes, multiple antimicrobial resistance genes, and mobile genetic elements. Notably, 77 isolates were highly resistant to gentamicin. Representative enterococcal isolates exerted toxic activities in both in vitro and in vivo models. Collectively, our findings suggest that probiotic enterococci may be harmful to hosts and pose a potential threat to public health.
format	article
author	Wenjiao Xu Yuwen Fang Qiao Hu Kui Zhu
author_facet	Wenjiao Xu Yuwen Fang Qiao Hu Kui Zhu
author_sort	Wenjiao Xu
title	Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
title_short	Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
title_full	Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
title_fullStr	Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
title_full_unstemmed	Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain
title_sort	emerging risks in food: probiotic enterococci pose a threat to public health through the food chain
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8a8013455d314ab9b5e8b6c31f421a70
work_keys_str_mv	AT wenjiaoxu emergingrisksinfoodprobioticenterococciposeathreattopublichealththroughthefoodchain AT yuwenfang emergingrisksinfoodprobioticenterococciposeathreattopublichealththroughthefoodchain AT qiaohu emergingrisksinfoodprobioticenterococciposeathreattopublichealththroughthefoodchain AT kuizhu emergingrisksinfoodprobioticenterococciposeathreattopublichealththroughthefoodchain
_version_	1718412177340104704

Emerging Risks in Food: Probiotic Enterococci Pose a Threat to Public Health through the Food Chain

Ejemplares similares