Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy

Decreased temperatures lengthen C. elegans lifespan by mechanisms that are not fully understood. Here the authors show that autophagy activation contributes to lifespan extension at low temperatures and that this involves adiponectin receptor PAQR-2 signaling.

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Autores principales:	Yuan-Li Chen, Jun Tao, Pei-Ji Zhao, Wei Tang, Jian-Ping Xu, Ke-Qin Zhang, Cheng-Gang Zou
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8a8c0d5d4e46418e944dff6275a69a07
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spelling	oai:doaj.org-article:8a8c0d5d4e46418e944dff6275a69a072021-12-02T16:57:34ZAdiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy10.1038/s41467-019-10475-82041-1723https://doaj.org/article/8a8c0d5d4e46418e944dff6275a69a072019-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10475-8https://doaj.org/toc/2041-1723Decreased temperatures lengthen C. elegans lifespan by mechanisms that are not fully understood. Here the authors show that autophagy activation contributes to lifespan extension at low temperatures and that this involves adiponectin receptor PAQR-2 signaling.Yuan-Li ChenJun TaoPei-Ji ZhaoWei TangJian-Ping XuKe-Qin ZhangCheng-Gang ZouNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Yuan-Li Chen Jun Tao Pei-Ji Zhao Wei Tang Jian-Ping Xu Ke-Qin Zhang Cheng-Gang Zou Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
description	Decreased temperatures lengthen C. elegans lifespan by mechanisms that are not fully understood. Here the authors show that autophagy activation contributes to lifespan extension at low temperatures and that this involves adiponectin receptor PAQR-2 signaling.
format	article
author	Yuan-Li Chen Jun Tao Pei-Ji Zhao Wei Tang Jian-Ping Xu Ke-Qin Zhang Cheng-Gang Zou
author_facet	Yuan-Li Chen Jun Tao Pei-Ji Zhao Wei Tang Jian-Ping Xu Ke-Qin Zhang Cheng-Gang Zou
author_sort	Yuan-Li Chen
title	Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
title_short	Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
title_full	Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
title_fullStr	Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
title_full_unstemmed	Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy
title_sort	adiponectin receptor paqr-2 signaling senses low temperature to promote c. elegans longevity by regulating autophagy
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/8a8c0d5d4e46418e944dff6275a69a07
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Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy

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