Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy

Decreased temperatures lengthen C. elegans lifespan by mechanisms that are not fully understood. Here the authors show that autophagy activation contributes to lifespan extension at low temperatures and that this involves adiponectin receptor PAQR-2 signaling.

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Bibliographic Details
Main Authors: Yuan-Li Chen, Jun Tao, Pei-Ji Zhao, Wei Tang, Jian-Ping Xu, Ke-Qin Zhang, Cheng-Gang Zou
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/8a8c0d5d4e46418e944dff6275a69a07
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