Proline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporter.

Trypanosoma cruzi, the etiological agent of Chagas' disease, has a metabolism largely based on the consumption of glucose and proline. This amino acid is essential for host cells infection and intracellular differentiation. In this work we identified a proline transporter (TcAAAP069) by yeasts...

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Auteurs principaux: Melisa Sayé, Mariana R Miranda, Fabio di Girolamo, María de los Milagros Cámara, Claudio A Pereira
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2014
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R
Q
Accès en ligne:https://doaj.org/article/8a989e441466437f9cd3defaec74020d
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