Pathology of mammary glands in women with reproductive disorders and chronic endometritis

Background. The last decades are devoted to the search for various factors leading to the development of benign breast diseases, which are the risk of breast cancer. In gynecological diseases, the frequency of benign processes in the mammary glands increases to 76-97.8 %. Aims: this research is devo...

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Autores principales:	I. N. Danusevich, L. F. Sholokhov, K. V. Sukhinina, E. B. Druzhinina, A. A. Semendyaev
Formato:	article
Lenguaje:	RU
Publicado:	Scientific Сentre for Family Health and Human Reproduction Problems 2018
Materias:	chronic endometritis reproductive disorders mammary glands hormones Science Q
Acceso en línea:	https://doaj.org/article/8abe41525405417290b89bee902e25b3
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spelling	oai:doaj.org-article:8abe41525405417290b89bee902e25b32021-11-23T06:14:40ZPathology of mammary glands in women with reproductive disorders and chronic endometritis2541-94202587-959610.29413/ABS.2018-3.3.2https://doaj.org/article/8abe41525405417290b89bee902e25b32018-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/578https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596Background. The last decades are devoted to the search for various factors leading to the development of benign breast diseases, which are the risk of breast cancer. In gynecological diseases, the frequency of benign processes in the mammary glands increases to 76-97.8 %. Aims: this research is devoted to the study of the prevalence and structure of breast pathology in women with chronic endometritis and reproductive disorders. Materials and methods. The study included patients with reproductive disorders: 50 patients with histological verification of the diagnosis of chronic endometritis and 50 patients without chronic endometritis. Hormonal examination was carried out using radioimmunoassay and immunoenzymatic methods. Methods of mathematical statistics implemented Statistica 6.1 (USA) were used parametric criteria: Student's t-test and Fisher's F-criterion, the nature of the distribution was estimated using the methods of Kolmogorov - Smirnov with a significance level smaller and equal to 5 % (p < 0.05). To confirm the fact that the observed differences between the products of A x D and B x C are not random, we used the х2 criterion. Results and conclusions. In women with chronic endometritis, the pathology of the mammary glands is characterized by the presence of ectasia of the ducts of the mammary gland; clinically, it is manifested by lactorrhea. Benign dysplasia of mammary glands is accompanied by the presence of hyperestrogenia, hypoprogesteronemia, which is typical for ovarian dysfunction. It is possible to use a pathogenetically reasonable combination correction: anti-inflammatory therapy and the use of gestagens in women with reproductive disorders and chronic endometritis.I. N. DanusevichL. F. SholokhovK. V. SukhininaE. B. DruzhininaA. A. SemendyaevScientific Сentre for Family Health and Human Reproduction Problemsarticlechronic endometritisreproductive disordersmammary glandshormonesScienceQRUActa Biomedica Scientifica, Vol 3, Iss 3, Pp 15-22 (2018)
institution	DOAJ
collection	DOAJ
language	RU
topic	chronic endometritis reproductive disorders mammary glands hormones Science Q
spellingShingle	chronic endometritis reproductive disorders mammary glands hormones Science Q I. N. Danusevich L. F. Sholokhov K. V. Sukhinina E. B. Druzhinina A. A. Semendyaev Pathology of mammary glands in women with reproductive disorders and chronic endometritis
description	Background. The last decades are devoted to the search for various factors leading to the development of benign breast diseases, which are the risk of breast cancer. In gynecological diseases, the frequency of benign processes in the mammary glands increases to 76-97.8 %. Aims: this research is devoted to the study of the prevalence and structure of breast pathology in women with chronic endometritis and reproductive disorders. Materials and methods. The study included patients with reproductive disorders: 50 patients with histological verification of the diagnosis of chronic endometritis and 50 patients without chronic endometritis. Hormonal examination was carried out using radioimmunoassay and immunoenzymatic methods. Methods of mathematical statistics implemented Statistica 6.1 (USA) were used parametric criteria: Student's t-test and Fisher's F-criterion, the nature of the distribution was estimated using the methods of Kolmogorov - Smirnov with a significance level smaller and equal to 5 % (p < 0.05). To confirm the fact that the observed differences between the products of A x D and B x C are not random, we used the х2 criterion. Results and conclusions. In women with chronic endometritis, the pathology of the mammary glands is characterized by the presence of ectasia of the ducts of the mammary gland; clinically, it is manifested by lactorrhea. Benign dysplasia of mammary glands is accompanied by the presence of hyperestrogenia, hypoprogesteronemia, which is typical for ovarian dysfunction. It is possible to use a pathogenetically reasonable combination correction: anti-inflammatory therapy and the use of gestagens in women with reproductive disorders and chronic endometritis.
format	article
author	I. N. Danusevich L. F. Sholokhov K. V. Sukhinina E. B. Druzhinina A. A. Semendyaev
author_facet	I. N. Danusevich L. F. Sholokhov K. V. Sukhinina E. B. Druzhinina A. A. Semendyaev
author_sort	I. N. Danusevich
title	Pathology of mammary glands in women with reproductive disorders and chronic endometritis
title_short	Pathology of mammary glands in women with reproductive disorders and chronic endometritis
title_full	Pathology of mammary glands in women with reproductive disorders and chronic endometritis
title_fullStr	Pathology of mammary glands in women with reproductive disorders and chronic endometritis
title_full_unstemmed	Pathology of mammary glands in women with reproductive disorders and chronic endometritis
title_sort	pathology of mammary glands in women with reproductive disorders and chronic endometritis
publisher	Scientific Сentre for Family Health and Human Reproduction Problems
publishDate	2018
url	https://doaj.org/article/8abe41525405417290b89bee902e25b3
work_keys_str_mv	AT indanusevich pathologyofmammaryglandsinwomenwithreproductivedisordersandchronicendometritis AT lfsholokhov pathologyofmammaryglandsinwomenwithreproductivedisordersandchronicendometritis AT kvsukhinina pathologyofmammaryglandsinwomenwithreproductivedisordersandchronicendometritis AT ebdruzhinina pathologyofmammaryglandsinwomenwithreproductivedisordersandchronicendometritis AT aasemendyaev pathologyofmammaryglandsinwomenwithreproductivedisordersandchronicendometritis
_version_	1718416957530701824

Pathology of mammary glands in women with reproductive disorders and chronic endometritis

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