Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.

We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseli...

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Autores principales:	Andreas D Flouris, Giorgos S Metsios, Andres E Carrillo, Athanasios Z Jamurtas, Polychronis D Stivaktakis, Manolis N Tzatzarakis, Aristidis M Tsatsakis, Yiannis Koutedakis
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8ac293e6333c48709c1b4198af26cdd7
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spelling	oai:doaj.org-article:8ac293e6333c48709c1b4198af26cdd72021-11-18T07:28:07ZRespiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.1932-620310.1371/journal.pone.0031880https://doaj.org/article/8ac293e6333c48709c1b4198af26cdd72012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22355401/pdf/?tool=EBIhttps://doaj.org/toc/1932-6203We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3- hours following 1-hour of SHS set at bar/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05). Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV(1) values at 0-hours dropped by 17.4%, while TNF-α increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-α and IFN-γ in men, as well as FEV(1)/FVC, percent predicted FEV(1), respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exertion in healthy nonsmokers for at least three hours following SHS.Andreas D FlourisGiorgos S MetsiosAndres E CarrilloAthanasios Z JamurtasPolychronis D StivaktakisManolis N TzatzarakisAristidis M TsatsakisYiannis KoutedakisPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 2, p e31880 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Andreas D Flouris Giorgos S Metsios Andres E Carrillo Athanasios Z Jamurtas Polychronis D Stivaktakis Manolis N Tzatzarakis Aristidis M Tsatsakis Yiannis Koutedakis Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
description	We assessed the cardiorespiratory and immune response to physical exertion following secondhand smoke (SHS) exposure through a randomized crossover experiment. Data were obtained from 16 (8 women) non-smoking adults during and following a maximal oxygen uptake cycling protocol administered at baseline and at 0-, 1-, and 3- hours following 1-hour of SHS set at bar/restaurant carbon monoxide levels. We found that SHS was associated with a 12% decrease in maximum power output, an 8.2% reduction in maximal oxygen consumption, a 6% increase in perceived exertion, and a 6.7% decrease in time to exhaustion (P<0.05). Moreover, at 0-hours almost all respiratory and immune variables measured were adversely affected (P<0.05). For instance, FEV(1) values at 0-hours dropped by 17.4%, while TNF-α increased by 90.1% (P<0.05). At 3-hours mean values of cotinine, perceived exertion and recovery systolic blood pressure in both sexes, IL4, TNF-α and IFN-γ in men, as well as FEV(1)/FVC, percent predicted FEV(1), respiratory rate, and tidal volume in women remained different compared to baseline (P<0.05). It is concluded that a 1-hour of SHS at bar/restaurant levels adversely affects the cardiorespiratory and immune response to maximal physical exertion in healthy nonsmokers for at least three hours following SHS.
format	article
author	Andreas D Flouris Giorgos S Metsios Andres E Carrillo Athanasios Z Jamurtas Polychronis D Stivaktakis Manolis N Tzatzarakis Aristidis M Tsatsakis Yiannis Koutedakis
author_facet	Andreas D Flouris Giorgos S Metsios Andres E Carrillo Athanasios Z Jamurtas Polychronis D Stivaktakis Manolis N Tzatzarakis Aristidis M Tsatsakis Yiannis Koutedakis
author_sort	Andreas D Flouris
title	Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
title_short	Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
title_full	Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
title_fullStr	Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
title_full_unstemmed	Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
title_sort	respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/8ac293e6333c48709c1b4198af26cdd7
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Respiratory and immune response to maximal physical exertion following exposure to secondhand smoke in healthy adults.

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