The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study
Mohammad Hosein Yazdanpanah,1,2 Sepideh Sayyadipoor,2 Sayed Reza Hojati,2 Amirreza Nikmanesh,2 Mojtaba Farjam,1 Reza Homayounfar1,3 1Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran; 2Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Dove Medical Press
2020
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/8ac2ea9bb3184e9c97c38237182e353b |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:8ac2ea9bb3184e9c97c38237182e353b |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:8ac2ea9bb3184e9c97c38237182e353b2021-12-02T10:32:13ZThe Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study1178-7007https://doaj.org/article/8ac2ea9bb3184e9c97c38237182e353b2020-08-01T00:00:00Zhttps://www.dovepress.com/the-association-of-metabolic-syndrome-and-its-components-with-electroc-peer-reviewed-article-DMSOhttps://doaj.org/toc/1178-7007Mohammad Hosein Yazdanpanah,1,2 Sepideh Sayyadipoor,2 Sayed Reza Hojati,2 Amirreza Nikmanesh,2 Mojtaba Farjam,1 Reza Homayounfar1,3 1Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran; 2Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran; 3National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranCorrespondence: Reza HomayounfarNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, IranTel +989125140840Email r_homayounfar@yahoo.comBackground: Metabolic syndrome (MetS) as a set of cardiac risk factors and its growing prevalence is one of the major concerns in different societies. In this study, we aimed to investigate the relationship between Mets and electrocardiogram (ECG) parameters and abnormalities as indicators for subclinical cardiovascular diseases (CVD).Methods: In this sub-analysis study, we used the data from Fasa PERSIAN Cohort Study which includes subjects age 35– 70 years. Subjects with available ECG data included in the study (n=7002) and subjects with missing data on MetS components and non-sinus rhythm ECG were excluded (n=44). The MetS definition based on the Adult Treatment Panel (ATP) III guidelines and also a 12-lead ECG was obtained from all participants.Results: Our study population (n=6958) showed a mean age of 48.60± 9.34 years and also 1656 (24.2%) subjects had MetS. Except for P duration, PR interval and S amplitude in men and P amplitude, S amplitude, Sokolow-Lyon Index, and QT interval in women, other ECG parameters differ significantly between subjects with and without Mets (P< 0.05). Also among ECG abnormalities, prolonged P duration (≥ 120ms), QRS duration (≥ 100ms), and QTc interval (> 450ms in male, > 470ms in female) had a significant association with MetS in the total population. Waist circumferences (WC) showed the most count of significant relationship with ECG parameters in both genders. In males, WC more than ATP cut-points had significant associations with prolonged P and QRS duration, and also blood pressure (BP) had significant associations with prolonged P and QRS durations and QTc interval. In females, the MetS component except triglyceride had at least a significant relationship with prolonged P and/or QRS duration.Conclusion: MetS and its component especially WC and BP were associated with ECG parameters and abnormalities. These associations with ECG as a marker of subclinical CVD showed the importance of MetS and each component in our population to monitor in the further longitudinal studies.Keywords: electrocardiogram, metabolic syndrome, P wave, QRS complex, QTc intervalYazdanpanah MHSayyadipoor SHojati SRNikmanesh AFarjam MHomayounfar RDove Medical Pressarticleelectrocardiogrammetabolic syndromep waveqrsqtc intervalSpecialties of internal medicineRC581-951ENDiabetes, Metabolic Syndrome and Obesity: Targets and Therapy, Vol Volume 13, Pp 2975-2987 (2020) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
electrocardiogram metabolic syndrome p wave qrs qtc interval Specialties of internal medicine RC581-951 |
| spellingShingle |
electrocardiogram metabolic syndrome p wave qrs qtc interval Specialties of internal medicine RC581-951 Yazdanpanah MH Sayyadipoor S Hojati SR Nikmanesh A Farjam M Homayounfar R The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| description |
Mohammad Hosein Yazdanpanah,1,2 Sepideh Sayyadipoor,2 Sayed Reza Hojati,2 Amirreza Nikmanesh,2 Mojtaba Farjam,1 Reza Homayounfar1,3 1Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran; 2Student Research Committee, Fasa University of Medical Sciences, Fasa, Iran; 3National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology, Shahid Beheshti University of Medical Sciences, Tehran, IranCorrespondence: Reza HomayounfarNoncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, IranTel +989125140840Email r_homayounfar@yahoo.comBackground: Metabolic syndrome (MetS) as a set of cardiac risk factors and its growing prevalence is one of the major concerns in different societies. In this study, we aimed to investigate the relationship between Mets and electrocardiogram (ECG) parameters and abnormalities as indicators for subclinical cardiovascular diseases (CVD).Methods: In this sub-analysis study, we used the data from Fasa PERSIAN Cohort Study which includes subjects age 35– 70 years. Subjects with available ECG data included in the study (n=7002) and subjects with missing data on MetS components and non-sinus rhythm ECG were excluded (n=44). The MetS definition based on the Adult Treatment Panel (ATP) III guidelines and also a 12-lead ECG was obtained from all participants.Results: Our study population (n=6958) showed a mean age of 48.60± 9.34 years and also 1656 (24.2%) subjects had MetS. Except for P duration, PR interval and S amplitude in men and P amplitude, S amplitude, Sokolow-Lyon Index, and QT interval in women, other ECG parameters differ significantly between subjects with and without Mets (P< 0.05). Also among ECG abnormalities, prolonged P duration (≥ 120ms), QRS duration (≥ 100ms), and QTc interval (> 450ms in male, > 470ms in female) had a significant association with MetS in the total population. Waist circumferences (WC) showed the most count of significant relationship with ECG parameters in both genders. In males, WC more than ATP cut-points had significant associations with prolonged P and QRS duration, and also blood pressure (BP) had significant associations with prolonged P and QRS durations and QTc interval. In females, the MetS component except triglyceride had at least a significant relationship with prolonged P and/or QRS duration.Conclusion: MetS and its component especially WC and BP were associated with ECG parameters and abnormalities. These associations with ECG as a marker of subclinical CVD showed the importance of MetS and each component in our population to monitor in the further longitudinal studies.Keywords: electrocardiogram, metabolic syndrome, P wave, QRS complex, QTc interval |
| format |
article |
| author |
Yazdanpanah MH Sayyadipoor S Hojati SR Nikmanesh A Farjam M Homayounfar R |
| author_facet |
Yazdanpanah MH Sayyadipoor S Hojati SR Nikmanesh A Farjam M Homayounfar R |
| author_sort |
Yazdanpanah MH |
| title |
The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| title_short |
The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| title_full |
The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| title_fullStr |
The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| title_full_unstemmed |
The Association of Metabolic Syndrome and Its Components with Electrocardiogram Parameters and Abnormalities Among an Iranian Rural Population: The Fasa PERSIAN Cohort Study |
| title_sort |
association of metabolic syndrome and its components with electrocardiogram parameters and abnormalities among an iranian rural population: the fasa persian cohort study |
| publisher |
Dove Medical Press |
| publishDate |
2020 |
| url |
https://doaj.org/article/8ac2ea9bb3184e9c97c38237182e353b |
| work_keys_str_mv |
AT yazdanpanahmh theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT sayyadipoors theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT hojatisr theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT nikmanesha theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT farjamm theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT homayounfarr theassociationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT yazdanpanahmh associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT sayyadipoors associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT hojatisr associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT nikmanesha associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT farjamm associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy AT homayounfarr associationofmetabolicsyndromeanditscomponentswithelectrocardiogramparametersandabnormalitiesamonganiranianruralpopulationthefasapersiancohortstudy |
| _version_ |
1718397067028594688 |