Single-component near-infrared optogenetic systems for gene transcription regulation

Current near-IR optogenetic systems to regulate transcription consist of a number of large protein components. Here the authors report a smaller single-component near-IR system, iLight, developed from a bacterial phytochrome that they use to control gene transcription in bacterial and mammalian cell...

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Autores principales: Andrii A. Kaberniuk, Mikhail Baloban, Mikhail V. Monakhov, Daria M. Shcherbakova, Vladislav V. Verkhusha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8acc6bf2a02e46e0b01259c899bbc2c0
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Sumario:Current near-IR optogenetic systems to regulate transcription consist of a number of large protein components. Here the authors report a smaller single-component near-IR system, iLight, developed from a bacterial phytochrome that they use to control gene transcription in bacterial and mammalian cells.