Single-component near-infrared optogenetic systems for gene transcription regulation

Current near-IR optogenetic systems to regulate transcription consist of a number of large protein components. Here the authors report a smaller single-component near-IR system, iLight, developed from a bacterial phytochrome that they use to control gene transcription in bacterial and mammalian cell...

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Autores principales: Andrii A. Kaberniuk, Mikhail Baloban, Mikhail V. Monakhov, Daria M. Shcherbakova, Vladislav V. Verkhusha
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8acc6bf2a02e46e0b01259c899bbc2c0
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spelling oai:doaj.org-article:8acc6bf2a02e46e0b01259c899bbc2c02021-12-02T17:14:22ZSingle-component near-infrared optogenetic systems for gene transcription regulation10.1038/s41467-021-24212-72041-1723https://doaj.org/article/8acc6bf2a02e46e0b01259c899bbc2c02021-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24212-7https://doaj.org/toc/2041-1723Current near-IR optogenetic systems to regulate transcription consist of a number of large protein components. Here the authors report a smaller single-component near-IR system, iLight, developed from a bacterial phytochrome that they use to control gene transcription in bacterial and mammalian cells.Andrii A. KaberniukMikhail BalobanMikhail V. MonakhovDaria M. ShcherbakovaVladislav V. VerkhushaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Andrii A. Kaberniuk
Mikhail Baloban
Mikhail V. Monakhov
Daria M. Shcherbakova
Vladislav V. Verkhusha
Single-component near-infrared optogenetic systems for gene transcription regulation
description Current near-IR optogenetic systems to regulate transcription consist of a number of large protein components. Here the authors report a smaller single-component near-IR system, iLight, developed from a bacterial phytochrome that they use to control gene transcription in bacterial and mammalian cells.
format article
author Andrii A. Kaberniuk
Mikhail Baloban
Mikhail V. Monakhov
Daria M. Shcherbakova
Vladislav V. Verkhusha
author_facet Andrii A. Kaberniuk
Mikhail Baloban
Mikhail V. Monakhov
Daria M. Shcherbakova
Vladislav V. Verkhusha
author_sort Andrii A. Kaberniuk
title Single-component near-infrared optogenetic systems for gene transcription regulation
title_short Single-component near-infrared optogenetic systems for gene transcription regulation
title_full Single-component near-infrared optogenetic systems for gene transcription regulation
title_fullStr Single-component near-infrared optogenetic systems for gene transcription regulation
title_full_unstemmed Single-component near-infrared optogenetic systems for gene transcription regulation
title_sort single-component near-infrared optogenetic systems for gene transcription regulation
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8acc6bf2a02e46e0b01259c899bbc2c0
work_keys_str_mv AT andriiakaberniuk singlecomponentnearinfraredoptogeneticsystemsforgenetranscriptionregulation
AT mikhailbaloban singlecomponentnearinfraredoptogeneticsystemsforgenetranscriptionregulation
AT mikhailvmonakhov singlecomponentnearinfraredoptogeneticsystemsforgenetranscriptionregulation
AT dariamshcherbakova singlecomponentnearinfraredoptogeneticsystemsforgenetranscriptionregulation
AT vladislavvverkhusha singlecomponentnearinfraredoptogeneticsystemsforgenetranscriptionregulation
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