Bonsai Gelsolin Survives Heat Induced Denaturation by Forming β-Amyloids which Leach Out Functional Monomer
Abstract Here, we report that minimal functional gelsolin i.e. fragment 28–161 can display F-actin depolymerizing property even after heating the protein to 80 °C. Small angle X-ray scattering (SAXS) data analysis confirmed that under Ca2+-free conditions, 28–161 associates into monomer to dimer and...
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Autores principales: | Maulik D. Badmalia, Pankaj Sharma, Shiv Pratap Singh Yadav, Shikha Singh, Neeraj Khatri, Renu Garg, Ashish |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Acceso en línea: | https://doaj.org/article/8ad1e21c804f41dca963fbf023acebc8 |
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