The anticancer plant triterpenoid, avicin D, regulates glucocorticoid receptor signaling: implications for cellular metabolism.

Avicins, a family of apoptotic triterpene electrophiles, are known to regulate cellular metabolism and energy homeostasis, by targeting the mitochondria. Having evolved from "ancient hopanoids," avicins bear a structural resemblance with glucocorticoids (GCs), which are the endogenous regu...

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Autores principales: Valsala Haridas, Zhi-Xiang Xu, Doug Kitchen, Anna Jiang, Peter Michels, Jordan U Gutterman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/8ad74154f81e4c93b8a40c720157dc4f
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