The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS

The GLP-1 receptor agonist, liraglutide, fails to slow disease progression in SOD1G93A and TDP-43Q331K transgenic mouse models of ALS

Abstract GLP-1 receptor agonists used for the treatment of diabetes, have shown some neuroprotective effects in cellular and animal models of Alzheimer’s disease (AD) and Parkinson’s disease (PD). There are currently few studies investigating GLP-1 receptor agonists in the treatment of ALS, where th...

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Autores principales: Amy Keerie, Heledd Brown-Wright, Isaac Kirkland, Andrew Grierson, James J. P. Alix, Christian Holscher, Richard J. Mead
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Medicine
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Acceso en línea:https://doaj.org/article/8ad89c55f0164a14a6f498f5d3f6500b
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