GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles

While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression pro...

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Autores principales: Botao Fa, Ting Wei, Yuan Zhou, Luke Johnston, Xin Yuan, Yanran Ma, Yue Zhang, Zhangsheng Yu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8ade08b8a643414e84ebe9771752ced7
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spelling oai:doaj.org-article:8ade08b8a643414e84ebe9771752ced72021-12-02T15:23:18ZGapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles10.1038/s41467-021-24489-82041-1723https://doaj.org/article/8ade08b8a643414e84ebe9771752ced72021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24489-8https://doaj.org/toc/2041-1723While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression profiles.Botao FaTing WeiYuan ZhouLuke JohnstonXin YuanYanran MaYue ZhangZhangsheng YuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Botao Fa
Ting Wei
Yuan Zhou
Luke Johnston
Xin Yuan
Yanran Ma
Yue Zhang
Zhangsheng Yu
GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
description While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression profiles.
format article
author Botao Fa
Ting Wei
Yuan Zhou
Luke Johnston
Xin Yuan
Yanran Ma
Yue Zhang
Zhangsheng Yu
author_facet Botao Fa
Ting Wei
Yuan Zhou
Luke Johnston
Xin Yuan
Yanran Ma
Yue Zhang
Zhangsheng Yu
author_sort Botao Fa
title GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
title_short GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
title_full GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
title_fullStr GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
title_full_unstemmed GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
title_sort gapclust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/8ade08b8a643414e84ebe9771752ced7
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