Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.
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Nature Portfolio
2017
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oai:doaj.org-article:8ae4a749c815404c9f04d03cdb561e1c2021-12-02T14:42:07ZChromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation10.1038/ncomms145272041-1723https://doaj.org/article/8ae4a749c815404c9f04d03cdb561e1c2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14527https://doaj.org/toc/2041-1723Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.Junwoo LeeEun Shik ChoiHogyu David SeoKeunsoo KangJoshua M. GilmoreLaurence FlorensMichael P. WashburnJoonho ChoeJerry L. WorkmanDaeyoup LeeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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Science Q Junwoo Lee Eun Shik Choi Hogyu David Seo Keunsoo Kang Joshua M. Gilmore Laurence Florens Michael P. Washburn Joonho Choe Jerry L. Workman Daeyoup Lee Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
description |
Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo. |
format |
article |
author |
Junwoo Lee Eun Shik Choi Hogyu David Seo Keunsoo Kang Joshua M. Gilmore Laurence Florens Michael P. Washburn Joonho Choe Jerry L. Workman Daeyoup Lee |
author_facet |
Junwoo Lee Eun Shik Choi Hogyu David Seo Keunsoo Kang Joshua M. Gilmore Laurence Florens Michael P. Washburn Joonho Choe Jerry L. Workman Daeyoup Lee |
author_sort |
Junwoo Lee |
title |
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
title_short |
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
title_full |
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
title_fullStr |
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
title_full_unstemmed |
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation |
title_sort |
chromatin remodeller fun30fft3 induces nucleosome disassembly to facilitate rna polymerase ii elongation |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/8ae4a749c815404c9f04d03cdb561e1c |
work_keys_str_mv |
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1718389821394649088 |