Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation

Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.

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Autores principales: Junwoo Lee, Eun Shik Choi, Hogyu David Seo, Keunsoo Kang, Joshua M. Gilmore, Laurence Florens, Michael P. Washburn, Joonho Choe, Jerry L. Workman, Daeyoup Lee
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/8ae4a749c815404c9f04d03cdb561e1c
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spelling oai:doaj.org-article:8ae4a749c815404c9f04d03cdb561e1c2021-12-02T14:42:07ZChromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation10.1038/ncomms145272041-1723https://doaj.org/article/8ae4a749c815404c9f04d03cdb561e1c2017-02-01T00:00:00Zhttps://doi.org/10.1038/ncomms14527https://doaj.org/toc/2041-1723Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.Junwoo LeeEun Shik ChoiHogyu David SeoKeunsoo KangJoshua M. GilmoreLaurence FlorensMichael P. WashburnJoonho ChoeJerry L. WorkmanDaeyoup LeeNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Junwoo Lee
Eun Shik Choi
Hogyu David Seo
Keunsoo Kang
Joshua M. Gilmore
Laurence Florens
Michael P. Washburn
Joonho Choe
Jerry L. Workman
Daeyoup Lee
Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
description Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.
format article
author Junwoo Lee
Eun Shik Choi
Hogyu David Seo
Keunsoo Kang
Joshua M. Gilmore
Laurence Florens
Michael P. Washburn
Joonho Choe
Jerry L. Workman
Daeyoup Lee
author_facet Junwoo Lee
Eun Shik Choi
Hogyu David Seo
Keunsoo Kang
Joshua M. Gilmore
Laurence Florens
Michael P. Washburn
Joonho Choe
Jerry L. Workman
Daeyoup Lee
author_sort Junwoo Lee
title Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
title_short Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
title_full Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
title_fullStr Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
title_full_unstemmed Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
title_sort chromatin remodeller fun30fft3 induces nucleosome disassembly to facilitate rna polymerase ii elongation
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/8ae4a749c815404c9f04d03cdb561e1c
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