High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resoluti...

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Autores principales:	Barbara Ruaro, Elisa Baratella, Paola Confalonieri, Barbara Wade, Cristina Marrocchio, Pietro Geri, Annalisa Busca, Riccardo Pozzan, Alessia Giovanna Andrisano, Maria Assunta Cova, Marco Confalonieri, Francesco Salton
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	systemic sclerosis-associated interstitial lung disease (SSc-ILD) interstitial lung disease (ILD) systemic sclerosis (SSc) high-resolution computed tomography (HRTC) pulmonary function tests (PFT) usual interstitial pneumonia (UIP) Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/8aeb5174020449afb6dd3529d3502e55
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spelling	oai:doaj.org-article:8aeb5174020449afb6dd3529d3502e552021-11-25T17:20:15ZHigh-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients10.3390/diagnostics111119602075-4418https://doaj.org/article/8aeb5174020449afb6dd3529d3502e552021-10-01T00:00:00Zhttps://www.mdpi.com/2075-4418/11/11/1960https://doaj.org/toc/2075-4418The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients.Barbara RuaroElisa BaratellaPaola ConfalonieriBarbara WadeCristina MarrocchioPietro GeriAnnalisa BuscaRiccardo PozzanAlessia Giovanna AndrisanoMaria Assunta CovaMarco ConfalonieriFrancesco SaltonMDPI AGarticlesystemic sclerosis-associated interstitial lung disease (SSc-ILD)interstitial lung disease (ILD)systemic sclerosis (SSc)high-resolution computed tomography (HRTC)pulmonary function tests (PFT)usual interstitial pneumonia (UIP)Medicine (General)R5-920ENDiagnostics, Vol 11, Iss 1960, p 1960 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	systemic sclerosis-associated interstitial lung disease (SSc-ILD) interstitial lung disease (ILD) systemic sclerosis (SSc) high-resolution computed tomography (HRTC) pulmonary function tests (PFT) usual interstitial pneumonia (UIP) Medicine (General) R5-920
spellingShingle	systemic sclerosis-associated interstitial lung disease (SSc-ILD) interstitial lung disease (ILD) systemic sclerosis (SSc) high-resolution computed tomography (HRTC) pulmonary function tests (PFT) usual interstitial pneumonia (UIP) Medicine (General) R5-920 Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
description	The diagnosis and classification of systemic sclerosis-associated interstitial lung disease (SSc-ILD) is essential to improve the prognosis of systemic sclerosis (SSc) patients. The risk-stratification of disease severity and follow-up requires a multidisciplinary approach, integrating high-resolution computed tomography (HRTC) of the lung, pulmonary function tests (PFT), along with clinical and symptomatic evaluations. The use of HRCT in detecting SSc-ILD is not so much based on a definitive validation, but rather reflects the widespread clinician recognition of dissatisfaction with other modalities. However, due to the heterogeneity of SSc-ILD and the potential absence of symptoms in early or mild disease, it is prudent to consider as many parameters as possible in the assessment and monitoring of newly diagnosed patients. An early diagnosis meets the primary goal, i.e., the prevention of disease progression. The current first line treatment regimens are mainly centered on immunosuppressive therapy. This review assesses the role HRCT plays in optimizing care and improving clinical outcomes in SSc-ILD patients.
format	article
author	Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton
author_facet	Barbara Ruaro Elisa Baratella Paola Confalonieri Barbara Wade Cristina Marrocchio Pietro Geri Annalisa Busca Riccardo Pozzan Alessia Giovanna Andrisano Maria Assunta Cova Marco Confalonieri Francesco Salton
author_sort	Barbara Ruaro
title	High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
title_short	High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
title_full	High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
title_fullStr	High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
title_full_unstemmed	High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients
title_sort	high-resolution computed tomography: lights and shadows in improving care for ssc-ild patients
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/8aeb5174020449afb6dd3529d3502e55
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High-Resolution Computed Tomography: Lights and Shadows in Improving Care for SSc-ILD Patients

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