Bi-directional cell-pericellular matrix interactions direct stem cell fate

Bi-directional cell-pericellular matrix interactions direct stem cell fate

3D hydrogels have provided information on the physical requirements of stem cell fate, but the contribution of interactions with the pericellular environment are under-explored. Here the authors show that pericellular matrix secreted by human bone marrow stromal cells (hMSC) embedded in a HA-based h...

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Autores principales: Silvia A. Ferreira, Meghna S. Motwani, Peter A. Faull, Alexis J. Seymour, Tracy T. L. Yu, Marjan Enayati, Dheraj K. Taheem, Christoph Salzlechner, Tabasom Haghighi, Ewa M. Kania, Oommen P. Oommen, Tarek Ahmed, Sandra Loaiza, Katarzyna Parzych, Francesco Dazzi, Oommen P. Varghese, Frederic Festy, Agamemnon E. Grigoriadis, Holger W. Auner, Ambrosius P. Snijders, Laurent Bozec, Eileen Gentleman
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Science
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Acceso en línea:https://doaj.org/article/8af8d8a81ddc405d9f52c6d4512ee247
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