ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity

The endosomal sorting complex required for transport-III (ESCRT-III) has been implicated in the packaging of HIV and HSV-1 viruses in the cytoplasm. Here the authors show that ESCRT-III proteins are required for the transport of HSV-1 nucleocapsids from nucleoplasm to cytosol through the nuclear env...

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Autores principales:	Jun Arii, Mizuki Watanabe, Fumio Maeda, Noriko Tokai-Nishizumi, Takahiro Chihara, Masayuki Miura, Yuhei Maruzuru, Naoto Koyanagi, Akihisa Kato, Yasushi Kawaguchi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8b01a42d133f40afba3056ad66d3756f
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spelling	oai:doaj.org-article:8b01a42d133f40afba3056ad66d3756f2021-12-02T16:56:40ZESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity10.1038/s41467-018-05889-92041-1723https://doaj.org/article/8b01a42d133f40afba3056ad66d3756f2018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05889-9https://doaj.org/toc/2041-1723The endosomal sorting complex required for transport-III (ESCRT-III) has been implicated in the packaging of HIV and HSV-1 viruses in the cytoplasm. Here the authors show that ESCRT-III proteins are required for the transport of HSV-1 nucleocapsids from nucleoplasm to cytosol through the nuclear envelope and confirm that the same mechanism is also used for the nucleocytoplasmic transport of RNP in Drosophila cells.Jun AriiMizuki WatanabeFumio MaedaNoriko Tokai-NishizumiTakahiro ChiharaMasayuki MiuraYuhei MaruzuruNaoto KoyanagiAkihisa KatoYasushi KawaguchiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jun Arii Mizuki Watanabe Fumio Maeda Noriko Tokai-Nishizumi Takahiro Chihara Masayuki Miura Yuhei Maruzuru Naoto Koyanagi Akihisa Kato Yasushi Kawaguchi ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
description	The endosomal sorting complex required for transport-III (ESCRT-III) has been implicated in the packaging of HIV and HSV-1 viruses in the cytoplasm. Here the authors show that ESCRT-III proteins are required for the transport of HSV-1 nucleocapsids from nucleoplasm to cytosol through the nuclear envelope and confirm that the same mechanism is also used for the nucleocytoplasmic transport of RNP in Drosophila cells.
format	article
author	Jun Arii Mizuki Watanabe Fumio Maeda Noriko Tokai-Nishizumi Takahiro Chihara Masayuki Miura Yuhei Maruzuru Naoto Koyanagi Akihisa Kato Yasushi Kawaguchi
author_facet	Jun Arii Mizuki Watanabe Fumio Maeda Noriko Tokai-Nishizumi Takahiro Chihara Masayuki Miura Yuhei Maruzuru Naoto Koyanagi Akihisa Kato Yasushi Kawaguchi
author_sort	Jun Arii
title	ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
title_short	ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
title_full	ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
title_fullStr	ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
title_full_unstemmed	ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity
title_sort	escrt-iii mediates budding across the inner nuclear membrane and regulates its integrity
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/8b01a42d133f40afba3056ad66d3756f
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ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity

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