A spinal neural circuitry for converting touch to itch sensation

Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (GRPR) neurons and form an integral part of th...

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Autores principales:	Sihan Chen, Xiao-Fei Gao, Yuxi Zhou, Ben-Long Liu, Xian-Yu Liu, Yufen Zhang, Devin M. Barry, Kun Liu, Yingfu Jiao, Rita Bardoni, Weifeng Yu, Zhou-Feng Chen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8b08af1fb3464132be8b8ad655383012
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spelling	oai:doaj.org-article:8b08af1fb3464132be8b8ad6553830122021-12-02T18:01:42ZA spinal neural circuitry for converting touch to itch sensation10.1038/s41467-020-18895-72041-1723https://doaj.org/article/8b08af1fb3464132be8b8ad6553830122020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18895-7https://doaj.org/toc/2041-1723Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (GRPR) neurons and form an integral part of the neural circuit underlying touch evoked itch.Sihan ChenXiao-Fei GaoYuxi ZhouBen-Long LiuXian-Yu LiuYufen ZhangDevin M. BarryKun LiuYingfu JiaoRita BardoniWeifeng YuZhou-Feng ChenNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sihan Chen Xiao-Fei Gao Yuxi Zhou Ben-Long Liu Xian-Yu Liu Yufen Zhang Devin M. Barry Kun Liu Yingfu Jiao Rita Bardoni Weifeng Yu Zhou-Feng Chen A spinal neural circuitry for converting touch to itch sensation
description	Light touch can sometimes induce unpleasant itch sensation but the neural correlates of this conversion are not well studied. Here, the authors provide evidence that Tac2 expressing spinal interneurons are connected to gastrin-releasing peptide receptor (GRPR) neurons and form an integral part of the neural circuit underlying touch evoked itch.
format	article
author	Sihan Chen Xiao-Fei Gao Yuxi Zhou Ben-Long Liu Xian-Yu Liu Yufen Zhang Devin M. Barry Kun Liu Yingfu Jiao Rita Bardoni Weifeng Yu Zhou-Feng Chen
author_facet	Sihan Chen Xiao-Fei Gao Yuxi Zhou Ben-Long Liu Xian-Yu Liu Yufen Zhang Devin M. Barry Kun Liu Yingfu Jiao Rita Bardoni Weifeng Yu Zhou-Feng Chen
author_sort	Sihan Chen
title	A spinal neural circuitry for converting touch to itch sensation
title_short	A spinal neural circuitry for converting touch to itch sensation
title_full	A spinal neural circuitry for converting touch to itch sensation
title_fullStr	A spinal neural circuitry for converting touch to itch sensation
title_full_unstemmed	A spinal neural circuitry for converting touch to itch sensation
title_sort	spinal neural circuitry for converting touch to itch sensation
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8b08af1fb3464132be8b8ad655383012
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A spinal neural circuitry for converting touch to itch sensation

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