Mutational burden and chromosomal aneuploidy synergistically predict survival from radiotherapy in non-small cell lung cancer

Here, the authors use whole exome sequencing to determine the effect of tumor mutational burden (TMB) and chromosomal aneuploidy (ANE) on survival outcomes of non-small cell lung cancer patients undergoing radiotherapy. The authors find that a higher TMB and lower ANE were correlated with better sur...

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Autores principales: Qingzhu Jia, Qian Chu, Anmei Zhang, Jing Yu, Fangfang Liu, Kaiyu Qian, Yu Xiao, Xue Wang, Ying Yang, Yi Zhao, Ji He, Guanghui Li, Yisong Y. Wan, Conghua Xie, Bo Zhu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/8b0b7a3e0aa74c93b93c8d76f943e280
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