Bacterial encapsulins as orthogonal compartments for mammalian cell engineering

Artificial compartments have been expressed in prokaryotes and yeast, but similar capabilities have been missing for mammalian cell engineering. Here the authors use bacterial encapsulins to engineer genetically controlled multifunctional orthogonal compartments in mammalian cells.

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Autores principales:	Felix Sigmund, Christoph Massner, Philipp Erdmann, Anja Stelzl, Hannes Rolbieski, Mitul Desai, Sarah Bricault, Tobias P. Wörner, Joost Snijder, Arie Geerlof, Helmut Fuchs, Martin Hrabĕ de Angelis, Albert J. R. Heck, Alan Jasanoff, Vasilis Ntziachristos, Jürgen Plitzko, Gil G. Westmeyer
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8b0b99fc471b4375adafc9f1ec3ae965
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spelling	oai:doaj.org-article:8b0b99fc471b4375adafc9f1ec3ae9652021-12-02T17:33:05ZBacterial encapsulins as orthogonal compartments for mammalian cell engineering10.1038/s41467-018-04227-32041-1723https://doaj.org/article/8b0b99fc471b4375adafc9f1ec3ae9652018-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-04227-3https://doaj.org/toc/2041-1723Artificial compartments have been expressed in prokaryotes and yeast, but similar capabilities have been missing for mammalian cell engineering. Here the authors use bacterial encapsulins to engineer genetically controlled multifunctional orthogonal compartments in mammalian cells.Felix SigmundChristoph MassnerPhilipp ErdmannAnja StelzlHannes RolbieskiMitul DesaiSarah BricaultTobias P. WörnerJoost SnijderArie GeerlofHelmut FuchsMartin Hrabĕ de AngelisAlbert J. R. HeckAlan JasanoffVasilis NtziachristosJürgen PlitzkoGil G. WestmeyerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Felix Sigmund Christoph Massner Philipp Erdmann Anja Stelzl Hannes Rolbieski Mitul Desai Sarah Bricault Tobias P. Wörner Joost Snijder Arie Geerlof Helmut Fuchs Martin Hrabĕ de Angelis Albert J. R. Heck Alan Jasanoff Vasilis Ntziachristos Jürgen Plitzko Gil G. Westmeyer Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
description	Artificial compartments have been expressed in prokaryotes and yeast, but similar capabilities have been missing for mammalian cell engineering. Here the authors use bacterial encapsulins to engineer genetically controlled multifunctional orthogonal compartments in mammalian cells.
format	article
author	Felix Sigmund Christoph Massner Philipp Erdmann Anja Stelzl Hannes Rolbieski Mitul Desai Sarah Bricault Tobias P. Wörner Joost Snijder Arie Geerlof Helmut Fuchs Martin Hrabĕ de Angelis Albert J. R. Heck Alan Jasanoff Vasilis Ntziachristos Jürgen Plitzko Gil G. Westmeyer
author_facet	Felix Sigmund Christoph Massner Philipp Erdmann Anja Stelzl Hannes Rolbieski Mitul Desai Sarah Bricault Tobias P. Wörner Joost Snijder Arie Geerlof Helmut Fuchs Martin Hrabĕ de Angelis Albert J. R. Heck Alan Jasanoff Vasilis Ntziachristos Jürgen Plitzko Gil G. Westmeyer
author_sort	Felix Sigmund
title	Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
title_short	Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
title_full	Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
title_fullStr	Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
title_full_unstemmed	Bacterial encapsulins as orthogonal compartments for mammalian cell engineering
title_sort	bacterial encapsulins as orthogonal compartments for mammalian cell engineering
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/8b0b99fc471b4375adafc9f1ec3ae965
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Bacterial encapsulins as orthogonal compartments for mammalian cell engineering

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