Developmental malformations resulting from high-dose maternal tamoxifen exposure in the mouse.
Tamoxifen is an estrogen receptor (ER) ligand with widespread use in clinical and basic research settings. Beyond its application in treating ER-positive cancer, tamoxifen has been co-opted into a powerful approach for temporal-specific genetic alteration. The use of tamoxifen-inducible Cre-recombin...
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Autores principales: | Miranda R Sun, Austin C Steward, Emma A Sweet, Alexander A Martin, Robert J Lipinski |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8b17ba8695694a41b57d7cab74fb038c |
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