Optineurin negatively regulates the induction of IFNbeta in response to RNA virus infection.
The innate immune response provides a critical defense against microbial infections, including viruses. These are recognised by pattern recognition receptors including Toll-like receptors (TLRs) and RIG-I like helicases (RLHs). Detection of virus triggers signalling cascades that induce transcriptio...
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| Auteurs principaux: | , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/8b1cdff4e5f94af59bc041f47ac7542d |
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