Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings

Abstract Background Dyspepsia is a common cause of physician visits. If and when endoscopy should be performed depend on the regions and the populations. This study aimed to identify the current risk factors predictive of upper gastrointestinal malignancy or peptic ulcer in China with high prevalenc...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yu Huang, Qian Gui, Huiyi Li, Xiaohua Long, Xiao Liang, Hong Lu
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Symptom Endoscopy Malignancy Peptic ulcer Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/8b20fcc514684b50be54011592638e64
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:8b20fcc514684b50be54011592638e64
record_format	dspace
spelling	oai:doaj.org-article:8b20fcc514684b50be54011592638e642021-11-28T12:14:59ZAge is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings10.1186/s12876-021-01951-x1471-230Xhttps://doaj.org/article/8b20fcc514684b50be54011592638e642021-11-01T00:00:00Zhttps://doi.org/10.1186/s12876-021-01951-xhttps://doaj.org/toc/1471-230XAbstract Background Dyspepsia is a common cause of physician visits. If and when endoscopy should be performed depend on the regions and the populations. This study aimed to identify the current risk factors predictive of upper gastrointestinal malignancy or peptic ulcer in China with high prevalence of gastric cancer. Methods A questionnaire was conducted among consecutive outpatients undergoing their first esophagogastroduodenoscopy for dyspepsia. Symptoms other than alarm symptoms in this study were defined as uncomplicated dyspepsia. Results 4310 outpatients (mean age 44, median 42, range 14–86) were included in the final analyses. Significant pathology was found in 13.8% (595/4310) patients including peptic ulcer (12.3%) and upper gastrointestinal malignancy (1.5%). Age, male sex and alarm symptoms were significantly associated with malignancy. The age cut-off identified for upper gastrointestinal malignancy was 56 years among patients with uncomplicated dyspepsia, which was similar to the combined cutoff of age and gender. Conclusions Age should be considered as the primary predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia. 56 could probably be the optimal age to identify those lesions in this population. Trial registration: Chictr.org (ChiCTR2000040775).Yu HuangQian GuiHuiyi LiXiaohua LongXiao LiangHong LuBMCarticleSymptomEndoscopyMalignancyPeptic ulcerDiseases of the digestive system. GastroenterologyRC799-869ENBMC Gastroenterology, Vol 21, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Symptom Endoscopy Malignancy Peptic ulcer Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Symptom Endoscopy Malignancy Peptic ulcer Diseases of the digestive system. Gastroenterology RC799-869 Yu Huang Qian Gui Huiyi Li Xiaohua Long Xiao Liang Hong Lu Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
description	Abstract Background Dyspepsia is a common cause of physician visits. If and when endoscopy should be performed depend on the regions and the populations. This study aimed to identify the current risk factors predictive of upper gastrointestinal malignancy or peptic ulcer in China with high prevalence of gastric cancer. Methods A questionnaire was conducted among consecutive outpatients undergoing their first esophagogastroduodenoscopy for dyspepsia. Symptoms other than alarm symptoms in this study were defined as uncomplicated dyspepsia. Results 4310 outpatients (mean age 44, median 42, range 14–86) were included in the final analyses. Significant pathology was found in 13.8% (595/4310) patients including peptic ulcer (12.3%) and upper gastrointestinal malignancy (1.5%). Age, male sex and alarm symptoms were significantly associated with malignancy. The age cut-off identified for upper gastrointestinal malignancy was 56 years among patients with uncomplicated dyspepsia, which was similar to the combined cutoff of age and gender. Conclusions Age should be considered as the primary predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia. 56 could probably be the optimal age to identify those lesions in this population. Trial registration: Chictr.org (ChiCTR2000040775).
format	article
author	Yu Huang Qian Gui Huiyi Li Xiaohua Long Xiao Liang Hong Lu
author_facet	Yu Huang Qian Gui Huiyi Li Xiaohua Long Xiao Liang Hong Lu
author_sort	Yu Huang
title	Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
title_short	Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
title_full	Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
title_fullStr	Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
title_full_unstemmed	Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
title_sort	age is the only predictor for upper gastrointestinal malignancy in chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings
publisher	BMC
publishDate	2021
url	https://doaj.org/article/8b20fcc514684b50be54011592638e64
work_keys_str_mv	AT yuhuang ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings AT qiangui ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings AT huiyili ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings AT xiaohualong ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings AT xiaoliang ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings AT honglu ageistheonlypredictorforuppergastrointestinalmalignancyinchinesepatientswithuncomplicateddyspepsiaaprospectiveinvestigationofendoscopicfindings
_version_	1718408087763681280

Age is the only predictor for upper gastrointestinal malignancy in Chinese patients with uncomplicated dyspepsia: a prospective investigation of endoscopic findings

Ejemplares similares