Inhibition of Sirt2 Alleviates Fibroblasts Activation and Pulmonary Fibrosis via Smad2/3 Pathway
Idiopathic pulmonary fibrosis (IPF) is a fatal disease with unknown cause and limited treatment options. Its mechanism needs to be further explored. Sirtuin2 (Sirt2), a nicotinamide adenine dinucleotide (NAD)-dependent deacetylase, has been proved to be involved in the fibrosis and inflammation in t...
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Format: | article |
Langue: | EN |
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Frontiers Media S.A.
2021
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Accès en ligne: | https://doaj.org/article/8b2b4f0dfeaa4c5fb0935762fc42269c |
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