Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephos...
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2020
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oai:doaj.org-article:8b32383d6ce641d7b7a43cd4cb33d8c12021-12-02T15:39:29ZCoupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis10.1038/s41467-020-20089-02041-1723https://doaj.org/article/8b32383d6ce641d7b7a43cd4cb33d8c12020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20089-0https://doaj.org/toc/2041-1723Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation.Yi-Zhe ZhangJianlong YuanLingrui ZhangChunxiang ChenYuhua WangGuiping ZhangLi PengSi-Si XieJing JiangJian-Kang ZhuJiamu DuCheng-Guo DuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020) |
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Science Q Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
description |
Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation. |
format |
article |
author |
Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan |
author_facet |
Yi-Zhe Zhang Jianlong Yuan Lingrui Zhang Chunxiang Chen Yuhua Wang Guiping Zhang Li Peng Si-Si Xie Jing Jiang Jian-Kang Zhu Jiamu Du Cheng-Guo Duan |
author_sort |
Yi-Zhe Zhang |
title |
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
title_short |
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
title_full |
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
title_fullStr |
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
title_full_unstemmed |
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis |
title_sort |
coupling of h3k27me3 recognition with transcriptional repression through the bah-phd-cpl2 complex in arabidopsis |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/8b32383d6ce641d7b7a43cd4cb33d8c1 |
work_keys_str_mv |
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