Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis

Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephos...

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Autores principales: Yi-Zhe Zhang, Jianlong Yuan, Lingrui Zhang, Chunxiang Chen, Yuhua Wang, Guiping Zhang, Li Peng, Si-Si Xie, Jing Jiang, Jian-Kang Zhu, Jiamu Du, Cheng-Guo Duan
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Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8b32383d6ce641d7b7a43cd4cb33d8c1
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spelling oai:doaj.org-article:8b32383d6ce641d7b7a43cd4cb33d8c12021-12-02T15:39:29ZCoupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis10.1038/s41467-020-20089-02041-1723https://doaj.org/article/8b32383d6ce641d7b7a43cd4cb33d8c12020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20089-0https://doaj.org/toc/2041-1723Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation.Yi-Zhe ZhangJianlong YuanLingrui ZhangChunxiang ChenYuhua WangGuiping ZhangLi PengSi-Si XieJing JiangJian-Kang ZhuJiamu DuCheng-Guo DuanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yi-Zhe Zhang
Jianlong Yuan
Lingrui Zhang
Chunxiang Chen
Yuhua Wang
Guiping Zhang
Li Peng
Si-Si Xie
Jing Jiang
Jian-Kang Zhu
Jiamu Du
Cheng-Guo Duan
Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
description Histone 3 Lys 27 trimethylation (H3K27me3) mediates epigenetic silencing of gene expression. Here, Zhang et al. show that in Arabidopsis, the BAH-domain H3K27me3-reader protein AIPP3 forms a complex with PHD proteins and CPL2, a plant-specific Pol II phosphatase, to inhibit Pol II activity by dephosphorylation.
format article
author Yi-Zhe Zhang
Jianlong Yuan
Lingrui Zhang
Chunxiang Chen
Yuhua Wang
Guiping Zhang
Li Peng
Si-Si Xie
Jing Jiang
Jian-Kang Zhu
Jiamu Du
Cheng-Guo Duan
author_facet Yi-Zhe Zhang
Jianlong Yuan
Lingrui Zhang
Chunxiang Chen
Yuhua Wang
Guiping Zhang
Li Peng
Si-Si Xie
Jing Jiang
Jian-Kang Zhu
Jiamu Du
Cheng-Guo Duan
author_sort Yi-Zhe Zhang
title Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
title_short Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
title_full Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
title_fullStr Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
title_full_unstemmed Coupling of H3K27me3 recognition with transcriptional repression through the BAH-PHD-CPL2 complex in Arabidopsis
title_sort coupling of h3k27me3 recognition with transcriptional repression through the bah-phd-cpl2 complex in arabidopsis
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8b32383d6ce641d7b7a43cd4cb33d8c1
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