MADRID+90 study on factors associated with longevity: Study design and preliminary data.

The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represen...

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Autores principales:	Miguel A Fernández-Blázquez, Teodoro Del Ser, Belén Frades-Payo, Marina Ávila-Villanueva, Meritxell Valentí-Soler, María T Benítez-Robredo, Antonio Bermejo-Aguña, Eduardo J Pedrero-Pérez, Javier Quilis-Sancho, Ana B Pastor, Concepción Fernández-Garrido, Sara Morales-Alonso, José M Diaz-Olalla, Nadine Correia Santos, Fernando Maestú, Jaime Gómez-Ramírez
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8b3cd74d639b4624980a1b14605605b7
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spelling	oai:doaj.org-article:8b3cd74d639b4624980a1b14605605b72021-11-25T06:19:12ZMADRID+90 study on factors associated with longevity: Study design and preliminary data.1932-620310.1371/journal.pone.0251796https://doaj.org/article/8b3cd74d639b4624980a1b14605605b72021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0251796https://doaj.org/toc/1932-6203The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer's type dementia. The project "Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid" (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies.Miguel A Fernández-BlázquezTeodoro Del SerBelén Frades-PayoMarina Ávila-VillanuevaMeritxell Valentí-SolerMaría T Benítez-RobredoAntonio Bermejo-AguñaEduardo J Pedrero-PérezJavier Quilis-SanchoAna B PastorConcepción Fernández-GarridoSara Morales-AlonsoJosé M Diaz-OlallaNadine Correia SantosFernando MaestúJaime Gómez-RamírezPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 5, p e0251796 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Miguel A Fernández-Blázquez Teodoro Del Ser Belén Frades-Payo Marina Ávila-Villanueva Meritxell Valentí-Soler María T Benítez-Robredo Antonio Bermejo-Aguña Eduardo J Pedrero-Pérez Javier Quilis-Sancho Ana B Pastor Concepción Fernández-Garrido Sara Morales-Alonso José M Diaz-Olalla Nadine Correia Santos Fernando Maestú Jaime Gómez-Ramírez MADRID+90 study on factors associated with longevity: Study design and preliminary data.
description	The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the next two decades. As this phenomenon will lead to an increase in illness and age-related dependency, the study of long-lived people represents an opportunity to explore which lifestyle factors are associated with healthy aging and which with the emergence of age-related diseases, especially Alzheimer's type dementia. The project "Factors associated with healthy and pathologically aging in a sample of elderly people over 90 in the city of Madrid" (MADRID+90) brings together a multidisciplinary research team in neurodegenerative diseases that includes experts in epidemiology, neurology, neuropsychology, neuroimaging and computational neuroscience. In the first phase of the project, a stratified random sampling was carried out according to the census of the city of Madrid followed by a survey conducted on 191 people aged 90 and over. This survey gathered information on demographics, clinical data, lifestyles and cognitive status. Here, the main results of that survey are showed. The second phase of the project aims to characterize individual trajectories in the course of either healthy and pathological aging, from a group of 50 subjects over 90 who will undergo a comprehensive clinical examination comprised of neurological and cognitive testing, MRI and EEG. The ultimate goal of the project is to characterize the biophysical and clinical profiles of a population that tends to receive little attention in the literature. A better understanding of the rapidly increasing group of nonagenarians will also help to design new policies that minimize the impact and future social and economic consequences of rapidly aging societies.
format	article
author	Miguel A Fernández-Blázquez Teodoro Del Ser Belén Frades-Payo Marina Ávila-Villanueva Meritxell Valentí-Soler María T Benítez-Robredo Antonio Bermejo-Aguña Eduardo J Pedrero-Pérez Javier Quilis-Sancho Ana B Pastor Concepción Fernández-Garrido Sara Morales-Alonso José M Diaz-Olalla Nadine Correia Santos Fernando Maestú Jaime Gómez-Ramírez
author_facet	Miguel A Fernández-Blázquez Teodoro Del Ser Belén Frades-Payo Marina Ávila-Villanueva Meritxell Valentí-Soler María T Benítez-Robredo Antonio Bermejo-Aguña Eduardo J Pedrero-Pérez Javier Quilis-Sancho Ana B Pastor Concepción Fernández-Garrido Sara Morales-Alonso José M Diaz-Olalla Nadine Correia Santos Fernando Maestú Jaime Gómez-Ramírez
author_sort	Miguel A Fernández-Blázquez
title	MADRID+90 study on factors associated with longevity: Study design and preliminary data.
title_short	MADRID+90 study on factors associated with longevity: Study design and preliminary data.
title_full	MADRID+90 study on factors associated with longevity: Study design and preliminary data.
title_fullStr	MADRID+90 study on factors associated with longevity: Study design and preliminary data.
title_full_unstemmed	MADRID+90 study on factors associated with longevity: Study design and preliminary data.
title_sort	madrid+90 study on factors associated with longevity: study design and preliminary data.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/8b3cd74d639b4624980a1b14605605b7
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MADRID+90 study on factors associated with longevity: Study design and preliminary data.

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