DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensable for higher order chromatin organization.

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Autores principales:	Stephan Nothjunge, Thomas G. Nührenberg, Björn A. Grüning, Stefanie A. Doppler, Sebastian Preissl, Martin Schwaderer, Carolin Rommel, Markus Krane, Lutz Hein, Ralf Gilsbach
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8b3e486861b4468d9a0816e1f96f830b
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spelling	oai:doaj.org-article:8b3e486861b4468d9a0816e1f96f830b2021-12-02T15:37:05ZDNA methylation signatures follow preformed chromatin compartments in cardiac myocytes10.1038/s41467-017-01724-92041-1723https://doaj.org/article/8b3e486861b4468d9a0816e1f96f830b2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01724-9https://doaj.org/toc/2041-1723Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensable for higher order chromatin organization.Stephan NothjungeThomas G. NührenbergBjörn A. GrüningStefanie A. DopplerSebastian PreisslMartin SchwadererCarolin RommelMarkus KraneLutz HeinRalf GilsbachNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Stephan Nothjunge Thomas G. Nührenberg Björn A. Grüning Stefanie A. Doppler Sebastian Preissl Martin Schwaderer Carolin Rommel Markus Krane Lutz Hein Ralf Gilsbach DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
description	Chromatin is organized in higher order A and B compartments, reflecting active and inactive chromatin. Here, the authors provide evidence that in cardiac myocytes DNA methylation is established in preformed chromatin compartments and may be dispensable for higher order chromatin organization.
format	article
author	Stephan Nothjunge Thomas G. Nührenberg Björn A. Grüning Stefanie A. Doppler Sebastian Preissl Martin Schwaderer Carolin Rommel Markus Krane Lutz Hein Ralf Gilsbach
author_facet	Stephan Nothjunge Thomas G. Nührenberg Björn A. Grüning Stefanie A. Doppler Sebastian Preissl Martin Schwaderer Carolin Rommel Markus Krane Lutz Hein Ralf Gilsbach
author_sort	Stephan Nothjunge
title	DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
title_short	DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
title_full	DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
title_fullStr	DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
title_full_unstemmed	DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes
title_sort	dna methylation signatures follow preformed chromatin compartments in cardiac myocytes
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8b3e486861b4468d9a0816e1f96f830b
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DNA methylation signatures follow preformed chromatin compartments in cardiac myocytes

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