Sleep quality among individuals with ketamine use and the mediating role of craving

Abstract Sleep problems are common in Taiwan. Poor sleep may be associated with many illnesses, including substance use disorders. Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems. Craving for ketamine is a risk factor for ke...

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Autores principales:	Cheng-Fang Yen, Huang-Chi Lin, Chih-Hung Ko, Hung-Chi Wu, Chih-Yao Hsu, Peng-Wei Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/8b4b0774be3b4d718bc9c03a6a8ee964
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spelling	oai:doaj.org-article:8b4b0774be3b4d718bc9c03a6a8ee9642021-12-02T15:10:06ZSleep quality among individuals with ketamine use and the mediating role of craving10.1038/s41598-020-77631-92045-2322https://doaj.org/article/8b4b0774be3b4d718bc9c03a6a8ee9642020-11-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-77631-9https://doaj.org/toc/2045-2322Abstract Sleep problems are common in Taiwan. Poor sleep may be associated with many illnesses, including substance use disorders. Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems. Craving for ketamine is a risk factor for ketamine use and relapse, and poor sleep quality may increase craving. This study aimed to explore the mediating effects of craving on the relationship between poor sleep quality and ketamine use. Demographic data, sleep quality, severity of dependence and craving were recorded for current ketamine users and abstinent ketamine users. Mediation analysis was used to examine the mediating effect of craving on the relationship between poor sleep and ketamine use. This study enrolled 414 current ketamine users with ketamine use disorder, 238 current ketamine users without ketamine use disorder, and 102 abstinent ketamine users with ketamine use disorder. Compared with healthy controls, all ketamine users had poor sleep quality. Poor sleep quality was associated with the initiation of and dependence on ketamine use. Craving can mediate the relationship between poor sleep quality and ketamine use. Poor sleep quality remains a problem for those abstaining from ketamine use. Poor sleep quality in ketamine users is an important issue because it is directly and indirectly through craving associated with ketamine use.Cheng-Fang YenHuang-Chi LinChih-Hung KoHung-Chi WuChih-Yao HsuPeng-Wei WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-6 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Cheng-Fang Yen Huang-Chi Lin Chih-Hung Ko Hung-Chi Wu Chih-Yao Hsu Peng-Wei Wang Sleep quality among individuals with ketamine use and the mediating role of craving
description	Abstract Sleep problems are common in Taiwan. Poor sleep may be associated with many illnesses, including substance use disorders. Ketamine use disorder has significantly increased in Taiwan in recent years and may lead to physical and cognitive problems. Craving for ketamine is a risk factor for ketamine use and relapse, and poor sleep quality may increase craving. This study aimed to explore the mediating effects of craving on the relationship between poor sleep quality and ketamine use. Demographic data, sleep quality, severity of dependence and craving were recorded for current ketamine users and abstinent ketamine users. Mediation analysis was used to examine the mediating effect of craving on the relationship between poor sleep and ketamine use. This study enrolled 414 current ketamine users with ketamine use disorder, 238 current ketamine users without ketamine use disorder, and 102 abstinent ketamine users with ketamine use disorder. Compared with healthy controls, all ketamine users had poor sleep quality. Poor sleep quality was associated with the initiation of and dependence on ketamine use. Craving can mediate the relationship between poor sleep quality and ketamine use. Poor sleep quality remains a problem for those abstaining from ketamine use. Poor sleep quality in ketamine users is an important issue because it is directly and indirectly through craving associated with ketamine use.
format	article
author	Cheng-Fang Yen Huang-Chi Lin Chih-Hung Ko Hung-Chi Wu Chih-Yao Hsu Peng-Wei Wang
author_facet	Cheng-Fang Yen Huang-Chi Lin Chih-Hung Ko Hung-Chi Wu Chih-Yao Hsu Peng-Wei Wang
author_sort	Cheng-Fang Yen
title	Sleep quality among individuals with ketamine use and the mediating role of craving
title_short	Sleep quality among individuals with ketamine use and the mediating role of craving
title_full	Sleep quality among individuals with ketamine use and the mediating role of craving
title_fullStr	Sleep quality among individuals with ketamine use and the mediating role of craving
title_full_unstemmed	Sleep quality among individuals with ketamine use and the mediating role of craving
title_sort	sleep quality among individuals with ketamine use and the mediating role of craving
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/8b4b0774be3b4d718bc9c03a6a8ee964
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Sleep quality among individuals with ketamine use and the mediating role of craving

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