Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
The genetic underpinnings of alcohol use disorder and consumption are incompletely understood. Here, the authors perform GWAS for Alcohol Use Disorder (AUD) Identification Test-Consumption scores and AUD diagnosis from electronic health records of 274,424 individuals and identify a total of 18 assoc...
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Nature Portfolio
2019
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oai:doaj.org-article:8b4e016a72ca43daaea6c0912c112a382021-12-02T16:57:23ZGenome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations10.1038/s41467-019-09480-82041-1723https://doaj.org/article/8b4e016a72ca43daaea6c0912c112a382019-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-09480-8https://doaj.org/toc/2041-1723The genetic underpinnings of alcohol use disorder and consumption are incompletely understood. Here, the authors perform GWAS for Alcohol Use Disorder (AUD) Identification Test-Consumption scores and AUD diagnosis from electronic health records of 274,424 individuals and identify a total of 18 associated loci.Henry R. KranzlerHang ZhouRachel L. KemberRachel Vickers SmithAmy C. JusticeScott DamrauerPhilip S. TsaoDerek KlarinAris BarasJeffrey ReidJohn OvertonDaniel J. RaderZhongshan ChengJanet P. TateWilliam C. BeckerJohn ConcatoKe XuRenato PolimantiHongyu ZhaoJoel GelernterNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-11 (2019) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Henry R. Kranzler Hang Zhou Rachel L. Kember Rachel Vickers Smith Amy C. Justice Scott Damrauer Philip S. Tsao Derek Klarin Aris Baras Jeffrey Reid John Overton Daniel J. Rader Zhongshan Cheng Janet P. Tate William C. Becker John Concato Ke Xu Renato Polimanti Hongyu Zhao Joel Gelernter Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| description |
The genetic underpinnings of alcohol use disorder and consumption are incompletely understood. Here, the authors perform GWAS for Alcohol Use Disorder (AUD) Identification Test-Consumption scores and AUD diagnosis from electronic health records of 274,424 individuals and identify a total of 18 associated loci. |
| format |
article |
| author |
Henry R. Kranzler Hang Zhou Rachel L. Kember Rachel Vickers Smith Amy C. Justice Scott Damrauer Philip S. Tsao Derek Klarin Aris Baras Jeffrey Reid John Overton Daniel J. Rader Zhongshan Cheng Janet P. Tate William C. Becker John Concato Ke Xu Renato Polimanti Hongyu Zhao Joel Gelernter |
| author_facet |
Henry R. Kranzler Hang Zhou Rachel L. Kember Rachel Vickers Smith Amy C. Justice Scott Damrauer Philip S. Tsao Derek Klarin Aris Baras Jeffrey Reid John Overton Daniel J. Rader Zhongshan Cheng Janet P. Tate William C. Becker John Concato Ke Xu Renato Polimanti Hongyu Zhao Joel Gelernter |
| author_sort |
Henry R. Kranzler |
| title |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| title_short |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| title_full |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| title_fullStr |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| title_full_unstemmed |
Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| title_sort |
genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations |
| publisher |
Nature Portfolio |
| publishDate |
2019 |
| url |
https://doaj.org/article/8b4e016a72ca43daaea6c0912c112a38 |
| work_keys_str_mv |
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