Surrogate endpoints for early-stage breast cancer: a review of the state of the art, controversies, and future prospects
Drug approval for early-stage breast cancer (EBC) has been historically granted in the context of registration trials based on adequate outcomes such as disease-free survival and overall survival. Improvements in long-term outcomes have made it more difficult to demonstrate the clinical benefit of a...
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Autores principales: | , , , , , |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
SAGE Publishing
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/8b548ce9bba54c9ca2cb0709f0aef8b1 |
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