Quantifying molecular bias in DNA data storage

DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.

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Autores principales: Yuan-Jyue Chen, Christopher N. Takahashi, Lee Organick, Callista Bee, Siena Dumas Ang, Patrick Weiss, Bill Peck, Georg Seelig, Luis Ceze, Karin Strauss
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/8b64e3fe84db42aa8ace116152d958c2
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spelling oai:doaj.org-article:8b64e3fe84db42aa8ace116152d958c22021-12-02T16:13:40ZQuantifying molecular bias in DNA data storage10.1038/s41467-020-16958-32041-1723https://doaj.org/article/8b64e3fe84db42aa8ace116152d958c22020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16958-3https://doaj.org/toc/2041-1723DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.Yuan-Jyue ChenChristopher N. TakahashiLee OrganickCallista BeeSiena Dumas AngPatrick WeissBill PeckGeorg SeeligLuis CezeKarin StraussNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yuan-Jyue Chen
Christopher N. Takahashi
Lee Organick
Callista Bee
Siena Dumas Ang
Patrick Weiss
Bill Peck
Georg Seelig
Luis Ceze
Karin Strauss
Quantifying molecular bias in DNA data storage
description DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.
format article
author Yuan-Jyue Chen
Christopher N. Takahashi
Lee Organick
Callista Bee
Siena Dumas Ang
Patrick Weiss
Bill Peck
Georg Seelig
Luis Ceze
Karin Strauss
author_facet Yuan-Jyue Chen
Christopher N. Takahashi
Lee Organick
Callista Bee
Siena Dumas Ang
Patrick Weiss
Bill Peck
Georg Seelig
Luis Ceze
Karin Strauss
author_sort Yuan-Jyue Chen
title Quantifying molecular bias in DNA data storage
title_short Quantifying molecular bias in DNA data storage
title_full Quantifying molecular bias in DNA data storage
title_fullStr Quantifying molecular bias in DNA data storage
title_full_unstemmed Quantifying molecular bias in DNA data storage
title_sort quantifying molecular bias in dna data storage
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/8b64e3fe84db42aa8ace116152d958c2
work_keys_str_mv AT yuanjyuechen quantifyingmolecularbiasindnadatastorage
AT christopherntakahashi quantifyingmolecularbiasindnadatastorage
AT leeorganick quantifyingmolecularbiasindnadatastorage
AT callistabee quantifyingmolecularbiasindnadatastorage
AT sienadumasang quantifyingmolecularbiasindnadatastorage
AT patrickweiss quantifyingmolecularbiasindnadatastorage
AT billpeck quantifyingmolecularbiasindnadatastorage
AT georgseelig quantifyingmolecularbiasindnadatastorage
AT luisceze quantifyingmolecularbiasindnadatastorage
AT karinstrauss quantifyingmolecularbiasindnadatastorage
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