Quantifying molecular bias in DNA data storage
DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.
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Nature Portfolio
2020
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oai:doaj.org-article:8b64e3fe84db42aa8ace116152d958c22021-12-02T16:13:40ZQuantifying molecular bias in DNA data storage10.1038/s41467-020-16958-32041-1723https://doaj.org/article/8b64e3fe84db42aa8ace116152d958c22020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16958-3https://doaj.org/toc/2041-1723DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification.Yuan-Jyue ChenChristopher N. TakahashiLee OrganickCallista BeeSiena Dumas AngPatrick WeissBill PeckGeorg SeeligLuis CezeKarin StraussNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020) |
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Science Q |
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Science Q Yuan-Jyue Chen Christopher N. Takahashi Lee Organick Callista Bee Siena Dumas Ang Patrick Weiss Bill Peck Georg Seelig Luis Ceze Karin Strauss Quantifying molecular bias in DNA data storage |
description |
DNA is an attractive digital data storing medium due to high information density and longevity. Here the authors use millions of sequences to investigate inherent biases in DNA synthesis and PCR amplification. |
format |
article |
author |
Yuan-Jyue Chen Christopher N. Takahashi Lee Organick Callista Bee Siena Dumas Ang Patrick Weiss Bill Peck Georg Seelig Luis Ceze Karin Strauss |
author_facet |
Yuan-Jyue Chen Christopher N. Takahashi Lee Organick Callista Bee Siena Dumas Ang Patrick Weiss Bill Peck Georg Seelig Luis Ceze Karin Strauss |
author_sort |
Yuan-Jyue Chen |
title |
Quantifying molecular bias in DNA data storage |
title_short |
Quantifying molecular bias in DNA data storage |
title_full |
Quantifying molecular bias in DNA data storage |
title_fullStr |
Quantifying molecular bias in DNA data storage |
title_full_unstemmed |
Quantifying molecular bias in DNA data storage |
title_sort |
quantifying molecular bias in dna data storage |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/8b64e3fe84db42aa8ace116152d958c2 |
work_keys_str_mv |
AT yuanjyuechen quantifyingmolecularbiasindnadatastorage AT christopherntakahashi quantifyingmolecularbiasindnadatastorage AT leeorganick quantifyingmolecularbiasindnadatastorage AT callistabee quantifyingmolecularbiasindnadatastorage AT sienadumasang quantifyingmolecularbiasindnadatastorage AT patrickweiss quantifyingmolecularbiasindnadatastorage AT billpeck quantifyingmolecularbiasindnadatastorage AT georgseelig quantifyingmolecularbiasindnadatastorage AT luisceze quantifyingmolecularbiasindnadatastorage AT karinstrauss quantifyingmolecularbiasindnadatastorage |
_version_ |
1718384361636626432 |