Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.
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Nature Portfolio
2016
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oai:doaj.org-article:8b762495f9ea4fd1bd661adc3e2c50e92021-12-02T17:32:05ZPhototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs10.1038/ncomms125012041-1723https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e92016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12501https://doaj.org/toc/2041-1723Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.Takashi OhtsukiShigeto KanzakiSae NishimuraYoshio KunihiroMasahiko SisidoKazunori WatanabeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016) |
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Science Q Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
description |
Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light. |
format |
article |
author |
Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe |
author_facet |
Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe |
author_sort |
Takashi Ohtsuki |
title |
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
title_short |
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
title_full |
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
title_fullStr |
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
title_full_unstemmed |
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs |
title_sort |
phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl trnas |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e9 |
work_keys_str_mv |
AT takashiohtsuki phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT shigetokanzaki phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT saenishimura phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT yoshiokunihiro phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT masahikosisido phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT kazunoriwatanabe phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas |
_version_ |
1718380382076796928 |