Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs

Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.

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Autores principales: Takashi Ohtsuki, Shigeto Kanzaki, Sae Nishimura, Yoshio Kunihiro, Masahiko Sisido, Kazunori Watanabe
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e9
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spelling oai:doaj.org-article:8b762495f9ea4fd1bd661adc3e2c50e92021-12-02T17:32:05ZPhototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs10.1038/ncomms125012041-1723https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e92016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12501https://doaj.org/toc/2041-1723Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.Takashi OhtsukiShigeto KanzakiSae NishimuraYoshio KunihiroMasahiko SisidoKazunori WatanabeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Takashi Ohtsuki
Shigeto Kanzaki
Sae Nishimura
Yoshio Kunihiro
Masahiko Sisido
Kazunori Watanabe
Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
description Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.
format article
author Takashi Ohtsuki
Shigeto Kanzaki
Sae Nishimura
Yoshio Kunihiro
Masahiko Sisido
Kazunori Watanabe
author_facet Takashi Ohtsuki
Shigeto Kanzaki
Sae Nishimura
Yoshio Kunihiro
Masahiko Sisido
Kazunori Watanabe
author_sort Takashi Ohtsuki
title Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_short Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_full Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_fullStr Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_full_unstemmed Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_sort phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl trnas
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e9
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