Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs

Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.

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Main Authors:	Takashi Ohtsuki, Shigeto Kanzaki, Sae Nishimura, Yoshio Kunihiro, Masahiko Sisido, Kazunori Watanabe
Format:	article
Language:	EN
Published:	Nature Portfolio 2016
Subjects:	Science Q
Online Access:	https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e9
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spelling	oai:doaj.org-article:8b762495f9ea4fd1bd661adc3e2c50e92021-12-02T17:32:05ZPhototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs10.1038/ncomms125012041-1723https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e92016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12501https://doaj.org/toc/2041-1723Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.Takashi OhtsukiShigeto KanzakiSae NishimuraYoshio KunihiroMasahiko SisidoKazunori WatanabeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
description	Spatiotemporal regulation of protein synthesis would advance studies into the consequences of localised protein translation in cells and tissues. Here, Ohtsuki et al.improve on an earlier caged-tRNA design to provide caged aminoacyl-tRNAs that are rapidly uncaged by visible light.
format	article
author	Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe
author_facet	Takashi Ohtsuki Shigeto Kanzaki Sae Nishimura Yoshio Kunihiro Masahiko Sisido Kazunori Watanabe
author_sort	Takashi Ohtsuki
title	Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_short	Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_full	Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_fullStr	Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_full_unstemmed	Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs
title_sort	phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl trnas
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/8b762495f9ea4fd1bd661adc3e2c50e9
work_keys_str_mv	AT takashiohtsuki phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT shigetokanzaki phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT saenishimura phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT yoshiokunihiro phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT masahikosisido phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas AT kazunoriwatanabe phototriggeredproteinsynthesesbyusing7diethylaminocoumarin4ylmethoxycarbonylcagedaminoacyltrnas
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Phototriggered protein syntheses by using (7-diethylaminocoumarin-4-yl)methoxycarbonyl-caged aminoacyl tRNAs

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