Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide

Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide

Abstract Elevated levels of plasma alpha1-antitrypsin (AAT) correlate with a poor prognosis of various cancers. Herein, we investigated effects of exogenous AAT on non-small lung cancer cell lines with high (H1975) and very low (H661) baseline expression of SERPINA1 gene encoding AAT protein. Compar...

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Autores principales: Natalie Schwarz, Srinu Tumpara, Sabine Wrenger, Evrim Ercetin, Jürg Hamacher, Tobias Welte, Sabina Janciauskiene
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
Materias:
Medicine
R
Science
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Acceso en línea:https://doaj.org/article/8b7d2f4e35ab458e8b9d5642d0b16ac7
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