Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.

Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells. Recently, its effectiveness against human hepatocellular carcinoma (HCC) cells both in vitro and in vivo was demonstrated. However, the mechanism...

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Autores principales: Johannes Klose, Metodi V Stankov, Moritz Kleine, Wolf Ramackers, Diana Panayotova-Dimitrova, Mark D Jäger, Jürgen Klempnauer, Michael Winkler, Hüseyin Bektas, Georg M N Behrens, Florian W R Vondran
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2014
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Acceso en línea:https://doaj.org/article/8b7dfc3009114d2ea2a0225d1fa21e6d
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