Inhibition of autophagic flux by salinomycin results in anti-cancer effect in hepatocellular carcinoma cells.
Salinomycin raised hope to be effective in anti-cancer therapies due to its capability to overcome apoptosis-resistance in several types of cancer cells. Recently, its effectiveness against human hepatocellular carcinoma (HCC) cells both in vitro and in vivo was demonstrated. However, the mechanism...
Guardado en:
Autores principales: | Johannes Klose, Metodi V Stankov, Moritz Kleine, Wolf Ramackers, Diana Panayotova-Dimitrova, Mark D Jäger, Jürgen Klempnauer, Michael Winkler, Hüseyin Bektas, Georg M N Behrens, Florian W R Vondran |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8b7dfc3009114d2ea2a0225d1fa21e6d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Salinomycin-Loaded Small-Molecule Nanoprodrugs Enhance Anticancer Activity in Hepatocellular Carcinoma
por: Wang J, et al.
Publicado: (2020) -
RORα Enhances Lysosomal Acidification and Autophagic Flux in the Hepatocytes
por: Hyeon‐Ji Kim, et al.
Publicado: (2021) -
The synergistic in vitro and in vivo antitumor effect of combination therapy with salinomycin and 5-fluorouracil against hepatocellular carcinoma.
por: Fan Wang, et al.
Publicado: (2014) -
Functional Autophagic Flux Regulates AgNP Uptake And The Internalized Nanoparticles Determine Tumor Cell Fate By Temporally Regulating Flux
por: Fageria L, et al.
Publicado: (2019) -
Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
por: Jiaming He, et al.
Publicado: (2021)