Silencing of miR-34a attenuates cardiac dysfunction in a setting of moderate, but not severe, hypertrophic cardiomyopathy.
Therapeutic inhibition of the miR-34 family (miR-34a,-b,-c), or miR-34a alone, have emerged as promising strategies for the treatment of cardiac pathology. However, before advancing these approaches further for potential entry into the clinic, a more comprehensive assessment of the therapeutic poten...
Guardado en:
Autores principales: | Bianca C Bernardo, Xiao-Ming Gao, Yow Keat Tham, Helen Kiriazis, Catherine E Winbanks, Jenny Y Y Ooi, Esther J H Boey, Susanna Obad, Sakari Kauppinen, Paul Gregorevic, Xiao-Jun Du, Ruby C Y Lin, Julie R McMullen |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2014
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Materias: | |
Acceso en línea: | https://doaj.org/article/8b902a46757b434fbe7761cf030d6d9f |
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