MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt

Vision: Microgravity may alter optic nerve and surrounding sheath Changes to the optic nerve and surrounding sheath during microgravity could explain why space flight is harmful to an astronaut’s vision. Darius Gerlach from the German Aerospace Center in Cologne and colleagues studied the tissue arc...

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Autores principales:	Darius A. Gerlach, Karina Marshall-Goebel, Khader M. Hasan, Larry A. Kramer, Noam Alperin, Joern Rittweger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Biotechnology TP248.13-248.65 Physiology QP1-981
Acceso en línea:	https://doaj.org/article/8b92afbf09f440a8b77a55d202d9e01f
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spelling	oai:doaj.org-article:8b92afbf09f440a8b77a55d202d9e01f2021-12-02T16:19:39ZMRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt10.1038/s41526-017-0023-y2373-8065https://doaj.org/article/8b92afbf09f440a8b77a55d202d9e01f2017-06-01T00:00:00Zhttps://doi.org/10.1038/s41526-017-0023-yhttps://doaj.org/toc/2373-8065Vision: Microgravity may alter optic nerve and surrounding sheath Changes to the optic nerve and surrounding sheath during microgravity could explain why space flight is harmful to an astronaut’s vision. Darius Gerlach from the German Aerospace Center in Cologne and colleagues studied the tissue architecture of the optic nerve and its surrounding sheath in nine healthy men who experienced head-down tilt, a commonly used ground-based model of weightlessness. Using a neuroimaging technique called diffusion tensor imaging, the researchers documented fluid dynamic changes wrought by the microgravity-like conditions that could be due to alterations in the volume and movement of cerebrospinal fluid within and around the optic nerve. The findings may help explain why many astronauts experience poorer vision after long-duration space flights, although more work is needed to explore the effects of true microgravity on the visual system.Darius A. GerlachKarina Marshall-GoebelKhader M. HasanLarry A. KramerNoam AlperinJoern RittwegerNature PortfolioarticleBiotechnologyTP248.13-248.65PhysiologyQP1-981ENnpj Microgravity, Vol 3, Iss 1, Pp 1-7 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biotechnology TP248.13-248.65 Physiology QP1-981
spellingShingle	Biotechnology TP248.13-248.65 Physiology QP1-981 Darius A. Gerlach Karina Marshall-Goebel Khader M. Hasan Larry A. Kramer Noam Alperin Joern Rittweger MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
description	Vision: Microgravity may alter optic nerve and surrounding sheath Changes to the optic nerve and surrounding sheath during microgravity could explain why space flight is harmful to an astronaut’s vision. Darius Gerlach from the German Aerospace Center in Cologne and colleagues studied the tissue architecture of the optic nerve and its surrounding sheath in nine healthy men who experienced head-down tilt, a commonly used ground-based model of weightlessness. Using a neuroimaging technique called diffusion tensor imaging, the researchers documented fluid dynamic changes wrought by the microgravity-like conditions that could be due to alterations in the volume and movement of cerebrospinal fluid within and around the optic nerve. The findings may help explain why many astronauts experience poorer vision after long-duration space flights, although more work is needed to explore the effects of true microgravity on the visual system.
format	article
author	Darius A. Gerlach Karina Marshall-Goebel Khader M. Hasan Larry A. Kramer Noam Alperin Joern Rittweger
author_facet	Darius A. Gerlach Karina Marshall-Goebel Khader M. Hasan Larry A. Kramer Noam Alperin Joern Rittweger
author_sort	Darius A. Gerlach
title	MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
title_short	MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
title_full	MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
title_fullStr	MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
title_full_unstemmed	MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
title_sort	mri-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/8b92afbf09f440a8b77a55d202d9e01f
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MRI-derived diffusion parameters in the human optic nerve and its surrounding sheath during head-down tilt

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