Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages

Microglia and peripheral myeloid cells are critically involved in the immunopathology of glioblastoma. Here the authors present single-cell sequencing data that assesses the phenotypic composition of CD11b + myeloid cells from a murine model of glioblastoma and suggest enhanced MHCII transcription w...

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Autores principales:	Natalia Ochocka, Pawel Segit, Kacper Adam Walentynowicz, Kamil Wojnicki, Salwador Cyranowski, Julian Swatler, Jakub Mieczkowski, Bozena Kaminska
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/8b9eb64aa0ea4022b732c0481f4e5d21
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spelling	oai:doaj.org-article:8b9eb64aa0ea4022b732c0481f4e5d212021-12-02T10:52:35ZSingle-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages10.1038/s41467-021-21407-w2041-1723https://doaj.org/article/8b9eb64aa0ea4022b732c0481f4e5d212021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21407-whttps://doaj.org/toc/2041-1723Microglia and peripheral myeloid cells are critically involved in the immunopathology of glioblastoma. Here the authors present single-cell sequencing data that assesses the phenotypic composition of CD11b + myeloid cells from a murine model of glioblastoma and suggest enhanced MHCII transcription which they additionally report from human cases of glioblastoma.Natalia OchockaPawel SegitKacper Adam WalentynowiczKamil WojnickiSalwador CyranowskiJulian SwatlerJakub MieczkowskiBozena KaminskaNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Natalia Ochocka Pawel Segit Kacper Adam Walentynowicz Kamil Wojnicki Salwador Cyranowski Julian Swatler Jakub Mieczkowski Bozena Kaminska Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
description	Microglia and peripheral myeloid cells are critically involved in the immunopathology of glioblastoma. Here the authors present single-cell sequencing data that assesses the phenotypic composition of CD11b + myeloid cells from a murine model of glioblastoma and suggest enhanced MHCII transcription which they additionally report from human cases of glioblastoma.
format	article
author	Natalia Ochocka Pawel Segit Kacper Adam Walentynowicz Kamil Wojnicki Salwador Cyranowski Julian Swatler Jakub Mieczkowski Bozena Kaminska
author_facet	Natalia Ochocka Pawel Segit Kacper Adam Walentynowicz Kamil Wojnicki Salwador Cyranowski Julian Swatler Jakub Mieczkowski Bozena Kaminska
author_sort	Natalia Ochocka
title	Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
title_short	Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
title_full	Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
title_fullStr	Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
title_full_unstemmed	Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
title_sort	single-cell rna sequencing reveals functional heterogeneity of glioma-associated brain macrophages
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/8b9eb64aa0ea4022b732c0481f4e5d21
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Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages

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