Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
Microglia and peripheral myeloid cells are critically involved in the immunopathology of glioblastoma. Here the authors present single-cell sequencing data that assesses the phenotypic composition of CD11b + myeloid cells from a murine model of glioblastoma and suggest enhanced MHCII transcription w...
Guardado en:
Autores principales: | Natalia Ochocka, Pawel Segit, Kacper Adam Walentynowicz, Kamil Wojnicki, Salwador Cyranowski, Julian Swatler, Jakub Mieczkowski, Bozena Kaminska |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/8b9eb64aa0ea4022b732c0481f4e5d21 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Characteristics of the alternative phenotype of microglia/macrophages and its modulation in experimental gliomas.
por: Konrad Gabrusiewicz, et al.
Publicado: (2011) -
Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas
por: Katrin Aslan, et al.
Publicado: (2020) -
The role of epigenetic modifications, long-range contacts, enhancers and topologically associating domains in the regulation of glioma grade-specific genes
por: Ilona E. Grabowicz, et al.
Publicado: (2021) -
Mapping chromatin accessibility and active regulatory elements reveals pathological mechanisms in human gliomas
por: Karolina Stępniak, et al.
Publicado: (2021) -
Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma
por: Erik Jung, et al.
Publicado: (2021)