Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.
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American Society for Microbiology
2021
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oai:doaj.org-article:8ba7479d5e1a46bf85e90d36970e35db2021-12-02T18:48:30ZEvolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character2379-507710.1128/mSystems.00244-21https://doaj.org/article/8ba7479d5e1a46bf85e90d36970e35db2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00244-21https://doaj.org/toc/2379-5077 Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.Nicolas CabanelIsabelle Rosinski-ChupinAdriana ChiarelliTatiana BotinMarta TatoRafael CantonPhilippe GlaserAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021) |
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Microbiology QR1-502 |
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Microbiology QR1-502 Nicolas Cabanel Isabelle Rosinski-Chupin Adriana Chiarelli Tatiana Botin Marta Tato Rafael Canton Philippe Glaser Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
description |
Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost. |
format |
article |
author |
Nicolas Cabanel Isabelle Rosinski-Chupin Adriana Chiarelli Tatiana Botin Marta Tato Rafael Canton Philippe Glaser |
author_facet |
Nicolas Cabanel Isabelle Rosinski-Chupin Adriana Chiarelli Tatiana Botin Marta Tato Rafael Canton Philippe Glaser |
author_sort |
Nicolas Cabanel |
title |
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
title_short |
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
title_full |
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
title_fullStr |
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
title_full_unstemmed |
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character |
title_sort |
evolution of vim-1-producing klebsiella pneumoniae isolates from a hospital outbreak reveals the genetic bases of the loss of the urease-positive identification character |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/8ba7479d5e1a46bf85e90d36970e35db |
work_keys_str_mv |
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