Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character

Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.

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Autores principales: Nicolas Cabanel, Isabelle Rosinski-Chupin, Adriana Chiarelli, Tatiana Botin, Marta Tato, Rafael Canton, Philippe Glaser
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2021
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Acceso en línea:https://doaj.org/article/8ba7479d5e1a46bf85e90d36970e35db
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spelling oai:doaj.org-article:8ba7479d5e1a46bf85e90d36970e35db2021-12-02T18:48:30ZEvolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character2379-507710.1128/mSystems.00244-21https://doaj.org/article/8ba7479d5e1a46bf85e90d36970e35db2021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00244-21https://doaj.org/toc/2379-5077 Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.Nicolas CabanelIsabelle Rosinski-ChupinAdriana ChiarelliTatiana BotinMarta TatoRafael CantonPhilippe GlaserAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Microbiology
QR1-502
spellingShingle Microbiology
QR1-502
Nicolas Cabanel
Isabelle Rosinski-Chupin
Adriana Chiarelli
Tatiana Botin
Marta Tato
Rafael Canton
Philippe Glaser
Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
description Evolution of multidrug-resistant bacterial pathogens occurs at multiple scales, in the patient, locally in the hospital, or more globally. Some mutations or gene acquisitions, for instance in response to antibiotic treatment, may be restricted to a single patient due to their high fitness cost.
format article
author Nicolas Cabanel
Isabelle Rosinski-Chupin
Adriana Chiarelli
Tatiana Botin
Marta Tato
Rafael Canton
Philippe Glaser
author_facet Nicolas Cabanel
Isabelle Rosinski-Chupin
Adriana Chiarelli
Tatiana Botin
Marta Tato
Rafael Canton
Philippe Glaser
author_sort Nicolas Cabanel
title Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
title_short Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
title_full Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
title_fullStr Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
title_full_unstemmed Evolution of VIM-1-Producing Klebsiella pneumoniae Isolates from a Hospital Outbreak Reveals the Genetic Bases of the Loss of the Urease-Positive Identification Character
title_sort evolution of vim-1-producing klebsiella pneumoniae isolates from a hospital outbreak reveals the genetic bases of the loss of the urease-positive identification character
publisher American Society for Microbiology
publishDate 2021
url https://doaj.org/article/8ba7479d5e1a46bf85e90d36970e35db
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