From Hi-C Contact Map to Three-Dimensional Organization of Interphase Human Chromosomes

The probability of two loci, separated by a certain genome length, being in contact can be inferred using the chromosome conformation capture (3C) method and related Hi-C experiments. How to go from the contact map, a matrix listing the mean contact probabilities between a large number of pairs of l...

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Autores principales: Guang Shi, D. Thirumalai
Formato: article
Lenguaje:EN
Publicado: American Physical Society 2021
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Acceso en línea:https://doaj.org/article/8ba8e8f50f624b8bb717f904f5bddc54
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