Relaxed sequence constraints favor mutational freedom in idiosyncratic metazoan mitochondrial tRNAs

Bilaterian mitochondria-encoded tRNA genes accumulate mutations at higher rates than their cytoplasmic tRNA counterparts, resulting in idiosyncratic structures. Here the authors suggest an evolutionary basis for the observed mutational freedom of mitochondrial (mt) tRNAs and reveal the associated co...

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Bibliographic Details
Main Authors: Bernhard Kuhle, Joseph Chihade, Paul Schimmel
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/8baf1f06210545d3a902682fc8ee32eb
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