Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease.
<h4>Background</h4>Huntington's disease is a devastating neurodegenerative condition for which there is no therapy to slow disease progression. The particular vulnerability of striatal medium spiny neurons to Huntington's pathology is hypothesized to result from transcriptional...
Enregistré dans:
| Auteurs principaux: | , , , , , |
|---|---|
| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
|
| Sujets: | |
| Accès en ligne: | https://doaj.org/article/8bb4ad0208bb4007b0bdcdbb45561208 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|