Regional transcriptome analysis of AMPA and GABAA receptor subunit expression generates E/I signatures of the human brain

Abstract Theoretical and experimental work has demonstrated that excitatory (E) and inhibitory (I) currents within cortical circuits stabilize to a balanced state. This E/I balance, observed from single neuron to network levels, has a fundamental role in proper brain function and its impairment has...

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Bibliographic Details
Main Authors: Kevin Shen, Tommaso Zeppillo, Agenor Limon
Format: article
Language:EN
Published: Nature Portfolio 2020
Subjects:
R
Q
Online Access:https://doaj.org/article/8bb5a3342ac040598e5e92620ab54c06
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